About: Cyclooxygenase Inhibitor

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Attributes	Values
rdf:type	Class
rdfs:label	Cyclooxygenase Inhibitor
rdfs:subClassOf	Nonsteroidal Antiinflammatory Drug Enzyme Inhibitor
Semantic_Type	Chemical Viewed Functionally
Preferred_Name	Cyclooxygenase Inhibitor
UMLS_CUI	C0085387
ALT_DEFINITION	A type of drug that is used to treat inflammation and pain, and is being studied in the prevention and treatment of cancer. COX inhibitors belong to the family of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs).NCI-GLOSS Compounds or agents that combine with cyclooxygenase (PROSTAGLANDIN-ENDOPEROXIDE SYNTHASE) and thereby prevent its substrate-enzyme combination with arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes.MSH2002_06_01
Legacy_Concept_Name	Cyclooxygenase_Inhibitor
CHEBI_ID	CHEBI:35544
FULL_SYN	cyclooxygenase inhibitorPTNCI-GLOSSCDR0000444986 COX InhibitorABNCI Cyclooxygenase InhibitorPTNCI Prostaglandin G/H Synthase InhibitorSYNCI Clyclooxygenases InhibitorSYNCI COX inhibitorPTNCI-GLOSSCDR0000444985
DEFINITION	Any agent that inhibits prostaglandin G/H synthase (cyclooxygenase or COX), an enzyme that catalyzes the production of prostanoids, including prostaglandins, prostacyclin and thromboxane, from arachidonic acid. Cyclooxygenase inhibitors are a type of non-steroidal anti-inflammatory drug.NCI
code	C1323
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0025664
is rdfs:subClassOf of	KETOROLAC ROFECOXIB Nimesulide Sulindac Sulfide INDOMETHACIN SODIUM NAPROXEN SODIUM Oxaprozin Potassium MELOXICAM Nitric Oxide-Releasing Acetylsalicylic Acid Derivative Ketorolac Tromethamine MECLOFENAMIC ACID NO-Releasing Ibuprofen Licofelone Lumiracoxib Mavacoxib Tilmacoxib Exisulind CELECOXIB VALDECOXIB ASPIRIN DICLOFENAC Oxaprozin Curcumin DICLOFENAC POTASSIUM DICLOFENAC SODIUM FLURBIPROFEN SODIUM Bardoxolone FLURBIPROFEN Etoricoxib Ibuprofen INDOMETHACIN FENOPROFEN Nitroflurbiprofen Nitrosulindac Fermented Wheat Germ Extract Ebselen Fenclofenac Fenclorac Fenclozic Acid Fenflumizole Feprazone Firocoxib Flosulide Pamicogrel Parecoxib Tomoxiprole Naproxen Deracoxib Piroxicam Cinnamate Apricoxib Diclofenac Sodium Gel PIROXICAM Cimicoxib Clofenamic Acid COX-2 Inhibitor Darbufelone Darbufelone Mesylate Fentiazac Loxoprofen Pravadoline Maleate Naproxcinod Pravadoline SULINDAC Bardoxolone Methyl

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