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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Valdecoxib
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Valdecoxib
UMLS_CUI
  • C0913246
CAS_Registry
  • 181695-72-7
Accepted_Therapeutic_Use_For
  • Osteoarthritis; rheumatoid arthritis; dysmenorrhea
FDA_UNII_Code
  • 2919279Q3W
Contributing_Source
  • FDA
ALT_DEFINITION
  • A substance that is being studied as a treatment for pain and other side effects of cancer therapy. It belongs to the family of drugs called COX-2 inhibitors.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 38320
PDQ_Closed_Trial_Search_ID
  • 38320
Chemical_Formula
  • C16H14N2O3S
Legacy_Concept_Name
  • Valdecoxib
CHEBI_ID
  • CHEBI:63634
FULL_SYN
  • 4-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonamideSNNCI
  • valdecoxibPTNCI-GLOSSCDR0000045021
  • 4-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonamidePTDCP50465
  • BextraBRNCI
  • VALDECOXIBPTFDA2919279Q3W
  • SC 65872CNNCI
  • ValdecoxibPTNCI
DEFINITION
  • A sulfonamide derivative and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic activities. Valdecoxib selectively binds to and inhibits cyclooxygenase (COX)-2, thereby preventing the conversion of arachidonic acid into prostaglandins, which are involved in the regulation of pain, inflammation, and fever. This NSAID does not inhibit COX-1 at therapeutic concentrations and therefore does not interfere with blood coagulation.NCI
code
  • C1869
sameAs
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