About: Flurbiprofen Sodium     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Flurbiprofen Sodium
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Flurbiprofen Sodium
UMLS_CUI
  • C0304658
CAS_Registry
  • 56767-76-1
FDA_UNII_Code
  • Z5B97MU9K4
Contributing_Source
  • FDA
Chemical_Formula
  • C15H12FO2.Na.2H2O
Legacy_Concept_Name
  • Flurbiprofen_Sodium
FULL_SYN
  • 2-Fluoro-alpha-methyl-4-diphenylacetic Acid Sodium SaltSNNCI
  • Flurbiprofen SodiumPTNCI
  • FLURBIPROFEN SODIUMPTFDAZ5B97MU9K4
DEFINITION
  • The sodium salt form of flurbiprofen, a propionic acid derivative and a member of the phenylalkanoic acid group of non-steroidal antiinflammatory drugs (NSAIDs) with analgesic, antiinflammatory and antipyretic effects. Flurbiprofen non-selectively binds to and inhibits cyclooxygenase (COX). This results in a reduction of arachidonic acid conversion into prostaglandins that are involved in the regulation of pain, inflammation and fever. This NSAID also inhibits carbonic anhydrase, thereby reducing the production of hydrogen and bicarbonate ions. Upon ocular administration, flurbiprofen may reduce bicarbonate ion concentrations leading to a decrease in the production of aqueous humor, thereby lowering intraocular pressure.NCI
code
  • C47997
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
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