About: Flurbiprofen     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Flurbiprofen
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Flurbiprofen
NSC_Code
  • 685701
UMLS_CUI
  • C0016377
CAS_Registry
  • 5104-49-4
FDA_UNII_Code
  • 5GRO578KLP
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 39245
PDQ_Closed_Trial_Search_ID
  • 39245
Chemical_Formula
  • C15H13FO2
Legacy_Concept_Name
  • Flurbiprofen
CHEBI_ID
  • CHEBI:5130
FULL_SYN
  • FLURBIPROFENPTFDA5GRO578KLP
  • FlurbiprofenPTNCI
  • AnsaidSYDTPNSC0685701
  • AnsaidBRNCI
  • 2-Fluoro-alpha-methyl[1,1'-biphenyl]-4-acetic AcidPTDCP01532
  • U-27,182CNNCI
  • 2-Fluoro-alpha-methyl[1,1'-biphenyl]-4-acetic AcidSNNCI
  • BTS 18,322CNNCI
DEFINITION
  • A derivative of propionic acid, and a phenylalkanoic acid derivative of non-steroidal antiinflammatory drugs (NSAIDs) with analgesic, antiinflammatory and antipyretic effects. Flurbiprofen non-selectively binds to and inhibits cyclooxygenase (COX). This results in a reduction of arachidonic acid conversion into prostaglandins that are involved in the regulation of pain, inflammation and fever. This NSAID also inhibits carbonic anhydrase, thereby reducing the production of hydrogen and bicarbonate ions. Upon ocular administration, flurbiprofen may reduce bicarbonate ion concentrations leading to a decrease in the production of aqueous humor, thereby lowering intraocular pressure.NCI
code
  • C508
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Free_Acid_Or_Base_Form of
is sameAs of
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