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AttributesValues
rdf:type
rdfs:label
  • Indomethacin Sodium
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Indomethacin Sodium
UMLS_CUI
  • C0982211
CAS_Registry
  • 74252-25-8
FDA_UNII_Code
  • 0IMX38M2GG
Contributing_Source
  • FDA
Chemical_Formula
  • C19H15ClNO4.Na.3H2O
Legacy_Concept_Name
  • Indomethacin_Sodium
FULL_SYN
  • Indocin I.V.BRNCI
  • Indomethacin SodiumPTNCI
  • INDOMETHACIN SODIUMPTFDA0IMX38M2GG
DEFINITION
  • The sodium salt of indomethacin, a methylated indole derivative with anti-inflammatory, analgesic-antipyretic and tocolytic effects. Indomethacin is a non-selective, reversible, and competitive inhibitor of cyclooxygenases 1 and 2, thereby blocking the conversion of arachidonic acid into prostaglandin precursors. Consequently, prostaglandin synthesis is decreased, and prostaglandin-mediated activities are prevented, including pain, inflammation, fever and uterine contraction.NCI
code
  • C47999
sameAs
is Has_Salt_Form of
is sameAs of
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