About: Diclofenac Sodium     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Diclofenac Sodium
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Diclofenac Sodium
UMLS_CUI
  • C0700583
CAS_Registry
  • 15307-79-6
Accepted_Therapeutic_Use_For
  • Osteoarthritis; Ophthalmic Inflammation
FDA_UNII_Code
  • QTG126297Q
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug that is used to treat the symptoms of rheumatoid arthritis and is being studied in the prevention and treatment of some types of skin cancer. It blocks substances that cause inflammation and pain. It may also prevent the growth of new blood vessels that tumors need to grow. It is a type of cyclooxygenase inhibitor, a type of nonsteroidal anti-inflammatory drug (NSAID), and a type of antiangiogenesis agent.NCI-GLOSS
Chemical_Formula
  • C14H10Cl2NO2.Na
Legacy_Concept_Name
  • Diclofenac_Sodium
CHEBI_ID
  • CHEBI:4509
FULL_SYN
  • diclofenac sodiumPTNCI-GLOSSCDR0000617660
  • Diclofenac SodiumPTDCP09109
  • 2-[(2,6-Dichlorophenyl)amino]benzeneacetic Acid Monosodium SaltSNNCI
  • Diclofenac SodiumPTNCI
  • DICLOFENAC SODIUMPTFDAQTG126297Q
  • GP 45840CNNCI
  • VoltarenPTNCI-GLOSSCDR0000617661
  • VoltarenBRNCI
DEFINITION
  • The sodium salt form of diclofenac, a benzene acetic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with analgesic, antipyretic and anti-inflammatory activity. Diclofenac sodium is a non-selective reversible and competitive inhibitor of cyclooxygenase (COX), subsequently blocking the conversion of arachidonic acid into prostaglandin precursors. This leads to an inhibition of the formation of prostaglandins that are involved in pain, inflammation and fever.NCI
code
  • C47984
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
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