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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Nimesulide
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Nimesulide
UMLS_CUI
  • C0132515
CAS_Registry
  • 51803-78-2
FDA_UNII_Code
  • V4TKW1454M
Contributing_Source
  • FDA
Chemical_Formula
  • C13H12N2O5S
Legacy_Concept_Name
  • Nimesulide
CHEBI_ID
  • CHEBI:44445
FULL_SYN
  • NimesulidePTDCP09322
  • N-(4-Nitro-2-phenoxyphenyl)methanesulfonamideSNNCI
  • NIMESULIDEPTFDAV4TKW1454M
  • NimesulidePTNCI
DEFINITION
  • A nonsteroidal arylsulfonamide with anti-inflammatory properties. Nimesulide inhibits the cyclooxygenase-mediated conversion of arachidonic acid to pro-inflammatory prostaglandins. Modestly selective for COX-2, this agent binds to the enzyme, thereby inactivating it. Nimesulide may inhibit some carcinogenic COX-2-related carcinogenic effects on xenobiotic metabolism, apoptosis, immune surveillance and angiogenesis (overexpressed COX-2 in tumor epithelial cells enhances production of vascular growth factors and the formation of capillary-like networks). (NCI04)NCI
code
  • C29842
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