About: Nonsteroidal Antiinflammatory Drug

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Attributes	Values
rdf:type	Class
rdfs:label	Nonsteroidal Antiinflammatory Drug
rdfs:subClassOf	Analgesic and Antipyretic
Semantic_Type	Chemical Viewed Functionally
Preferred_Name	Nonsteroidal Antiinflammatory Drug
UMLS_CUI	C0003211
Accepted_Therapeutic_Use_For	Inflammation
ALT_DEFINITION	A group of drugs that decrease fever, swelling, pain, and redness.NCI-GLOSS
Legacy_Concept_Name	Nonsteroidal_Antiinflammatory_Drug
CHEBI_ID	CHEBI:35475
FULL_SYN	Nonsteroidal Antiinflammatory DrugPTNCI NSAIDsPTNCI-GLOSSCDR0000045807 NSAIDABNCI nonsteroidal anti-inflammatory drugPTNCI-GLOSSCDR0000044481
DEFINITION	Anti-inflammatory agents that are not steroids. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They are used primarily in the treatment of chronic arthritic conditions and certain soft tissue disorders associated with pain and inflammation. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. Certain NSAIDs also may inhibit lipoxygenase enzymes or phospholipase C or may modulate T-cell function. (MeSH)NCI
code	C257
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0001335
is rdfs:subClassOf of	MESALAMINE SULFASALAZINE KETOPROFEN MECLOFENAMATE SODIUM MEFENAMIC ACID SALICYLIC ACID TOLMETIN SODIUM Zomepirac Sodium Isofezolac Isonixin Isoprazone Lexofenac Lonazolac Lotifazole Mabuprofen MAGNESIUM SALICYLATE Metamfazone Metanixin Metazamide Mofezolac Morazone NEPAFENAC Oxepinac PHENYLBUTAZONE Pimetacin Sulprosal Triflumidate Xenbucin Xenipentone Zidometacin Zoliprofen Zomepirac Protizinic Acid Ramifenazone Salverine Tifurac Sodium Lornoxicam Strinoline Lobenzarit Sodium Ticalopride Varespladib Sodium Ipsalazide Meseclazone Mofebutazone Nimazone Suxibuzone Tenidap Sodium Nicotredole Oxyphenbutazone Anhydrous Lithium Salicylate Oxametacin Pralnacasan Nictindole Nifenazone Niflumic Acid Nixylic Acid Talmetacin Tazeprofen Tianafac Tilnoprofen Arbamel Tinoridine Tioxaprofen Trifezolac Indopine Hydrochloride Iodoantipyrine Magnesium Salicylate Anhydrous Kebuzone Isamfazone Isoxicam Lobuprofen Lofemizole Lonaprofen Lufuradom METHYL SALICYLATE Robenacoxib Prifelone Lofemizole Hydrochloride Nedocromil Calcium Indobufen Indoprofen Isoprofen Mebenoside Naproxol

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