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AttributesValues
rdf:type
rdfs:label
  • Ibuprofen
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Ibuprofen
NSC_Code
  • 256857
UMLS_CUI
  • C0593507
CAS_Registry
  • 15687-27-1
FDA_UNII_Code
  • WK2XYI10QM
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug used to treat fever, swelling, pain, and redness by preventing the body from making a substance that causes inflammation. It is a type of nonsteroidal anti-inflammatory drug (NSAID).NCI-GLOSS
  • A nonsteroidal anti-inflammatory agent with analgesic properties used in the therapy of rheumatism and arthritis.MSH2002_06_01
PDQ_Open_Trial_Search_ID
  • 40475
PDQ_Closed_Trial_Search_ID
  • 40475
Chemical_Formula
  • C13H18O2
Legacy_Concept_Name
  • Ibuprofen
CHEBI_ID
  • CHEBI:5855
FULL_SYN
  • Benzeneacetic Acid, Alpha-methyl-4-(2-methylpropyl)-SNNCI
  • (.+ -.)-p-Isobutylhydratropic acidSYDTPNSC0256857
  • IbuprofenPTDCP00803
  • p-Isobutylhydratropic acidSYDTPNSC0256857
  • MotrinSYDTPNSC0256857
  • AdvilPTNCI-GLOSSCDR0000613724
  • p-Isobutylhydratropic AcidSNNCI
  • MotrinPTNCI-GLOSSCDR0000613512
  • IBUPROFENPTFDAWK2XYI10QM
  • MotrinBRNCI
  • IbuprofenPTNCI
  • ibuprofenPTNCI-GLOSSCDR0000613511
DEFINITION
  • A propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. This leads to decreased prostaglandin synthesis, by prostaglandin synthase, the main physiologic effect of ibuprofen. Ibuprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation. (NCI05)NCI
code
  • C561
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is sameAs of
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