About: Cephalosporin Antibiotic

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Attributes	Values
rdf:type	Class
rdfs:label	Cephalosporin Antibiotic
rdfs:subClassOf	Monobactams
Semantic_Type	Chemical Viewed Functionally
Preferred_Name	Cephalosporin Antibiotic
UMLS_CUI	C2266959
ALT_DEFINITION	A drug used to treat bacterial infections. It belongs to the family of drugs called antibiotics.NCI-GLOSS
Legacy_Concept_Name	Cephalosporin_Antibiotic
CHEBI_ID	CHEBI:23066
FULL_SYN	Cephalosporin AntibioticPTNCI CephalosporinsSYNCI cephalosporinPTNCI-GLOSSCDR0000046676
DEFINITION	A synthetic or semi-synthetic beta-lactam antibiotic derived from Acremonium (Cephalosporium) fungi with bactericidal activity. Cephalosporin antibiotics bind to and inactivate penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis.NCI
code	C357
sameAs	Cephalosporin Antibacterial
is rdfs:subClassOf of	Loracarbef Loracarbef Anhydrous MOXALACTAM DISODIUM MOXALACTAM CEFEPIME HYDROCHLORIDE CEFIXIME CEFOTAXIME SODIUM CEFACLOR CEFADROXIL CEFAZOLIN CEFDINIR Cefoxitin Sodium CEFPODOXIME PROXETIL CEFPROZIL CEFUROXIME AXETIL CEFAMANDOLE CEFOTAXIME Ceftazidime Sodium CEPHALEXIN CEPHALOTHIN SODIUM CEFDITOREN PIVOXIL CEFOPERAZONE SODIUM CEFORANIDE Cefotetan Disodium CEFTIZOXIME SODIUM CEFUROXIME SODIUM CEPHAPIRIN SODIUM CEPHRADINE Cefadroxil Hemihydrate CEFAMANDOLE NAFATE Cefamandole Sodium CEFAZOLIN SODIUM CEPHALEXIN HYDROCHLORIDE Cephradine Dihydrate Cephradine Monohydrate CEFOPERAZONE CEFOTETAN CEFOXITIN CEFTIBUTEN Ceftibuten Dihydrate CEFTIZOXIME CEFUROXIME CEPHAPIRIN CEFTRIAXONE CEPHALOTHIN CEFEPIME Cefmenoxime Cefmenoxime Hydrochloride CEFMETAZOLE CEFMETAZOLE SODIUM CEFONICID CEFONICID SODIUM Cefotiam Cefotiam Hydrochloride Cefpiramide Cefpiramide Sodium Cefpodoxime Ceftobiprole Cephaloglycin Flomoxef CEFTAZIDIME Ceftobiprole Medocaril CEFDITOREN Cefaclor Anhydrous Cefluprenam Cefovecin Cefovecin Sodium Cefsumide Ceftezole Cefaloram Cefazedone Cefcanel Cefcanel Daloxate Cefcapene Cefdaloxime Cefedrolor Cefempidone Cefetamet Cefetecol Cefetrizole Cefivitril Cefmatilen Cefminox Cefonicid Monosodium Cefoxazole

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