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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Cephradine
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Cephradine
UMLS_CUI
  • C0007738
CAS_Registry
  • 31828-50-9
FDA_UNII_Code
  • F1BC02I72W
Contributing_Source
  • FDA
Legacy_Concept_Name
  • Cephradine
FULL_SYN
  • SK&F D-39304CNNCI
  • (6R,7R)-7-((R)-2-Amino-2-(1,4-cyclohexadien-1-yl)acetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic AcidSNNCI
  • CEPHRADINE, UNSPECIFIED HYDRATEPTFDAF1BC02I72W
  • AnsporBRNCI
  • VelosefBRNCI
  • SQ 11436CNNCI
  • CefradineSYNCI
  • CephradinePTNCI
DEFINITION
  • A beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cephradine binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. PBPs participate in the terminal stages of assembling the bacterial cell wall, and in reshaping the cell wall during cell division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.NCI
code
  • C47441
sameAs
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