About: Cefadroxil     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Cefadroxil
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Antibiotic
  • Organic Chemical
Preferred_Name
  • Cefadroxil
UMLS_CUI
  • C0007538
CAS_Registry
  • 66592-87-8
FDA_UNII_Code
  • 280111G160
Contributing_Source
  • FDA
Chemical_Formula
  • C16H17N3O5S.H2O
Legacy_Concept_Name
  • Cefadroxil
CHEBI_ID
  • CHEBI:53667
FULL_SYN
  • (6R,7R)-7-(((2R)-Amino(4-hydroxyphenyl)acetyl)amino)-3-methyl-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic AcidSNNCI
  • DuricefBRNCI
  • CEFADROXILPTFDA280111G160
  • CefadroxilPTNCI
DEFINITION
  • A semi-synthetic, beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cefadroxil binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.NCI
code
  • C28912
sameAs
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