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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Ceftibuten Dihydrate
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Ceftibuten Dihydrate
UMLS_CUI
  • C0591239
CAS_Registry
  • 118081-34-8
FDA_UNII_Code
  • 62F4443RWP
Contributing_Source
  • FDA
Chemical_Formula
  • C15H14N4O6S2.2H2O
Legacy_Concept_Name
  • Ceftibuten_Dihydrate
CHEBI_ID
  • CHEBI:34618
FULL_SYN
  • CEFTIBUTEN DIHYDRATEPTFDA62F4443RWP
  • CedaxBRNCI
  • Ceftibuten DihydratePTNCI
DEFINITION
  • The dihydrate form of ceftibuten, a semisynthetic, beta-lactamase-stable, third-generation cephalosporin with antibacterial activity. Ceftibuten binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.NCI
code
  • C61667
sameAs
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