About: Cefpodoxime Proxetil     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Cefpodoxime Proxetil
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Antibiotic
  • Organic Chemical
Preferred_Name
  • Cefpodoxime Proxetil
UMLS_CUI
  • C0108938
CAS_Registry
  • 87239-81-4
FDA_UNII_Code
  • 2TB00A1Z7N
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 455227
PDQ_Closed_Trial_Search_ID
  • 455227
Legacy_Concept_Name
  • Cefpodoxime
CHEBI_ID
  • CHEBI:3505
FULL_SYN
  • CEFPODOXIME PROXETILPTFDA2TB00A1Z7N
  • VantinBRNCI
  • Cefpodoxime ProxetilPTNCI
DEFINITION
  • A third generation semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity. Cefpodoxime's effect is dependent on its binding to penicillin-binding proteins (PBPs) located in the bacterial cytoplasmic membrane. Binding results in the inhibition of the transpeptidase enzymes, thereby preventing cross-linking of the pentaglycine bridge with the fourth residue of the pentapeptide and interrupting consequent synthesis of peptidoglycan chains. As a result, cefpodoxime inhibits bacterial septum and cell wall synthesis formation.NCI
code
  • C28916
sameAs
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