About: Cefpodoxime     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Cefpodoxime
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Cefpodoxime
UMLS_CUI
  • C0055011
CAS_Registry
  • 80210-62-4
FDA_UNII_Code
  • 7R4F94TVGY
Contributing_Source
  • FDA
Chemical_Formula
  • C15H17N5O6S2
Legacy_Concept_Name
  • Cefpodoxime_Base
CHEBI_ID
  • CHEBI:3504
  • CHEBI:606443
FULL_SYN
  • CefpodoximePTNCI
  • CEFPODOXIMEPTFDA7R4F94TVGY
DEFINITION
  • A third generation semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity. Cefpodoxime's effect is dependent on its binding to penicillin-binding proteins (PBPs) located in the bacterial cytoplasmic membrane. Binding results in the inhibition of the transpeptidase enzymes, thereby preventing cross-linking of the pentaglycine bridge with the fourth residue of the pentapeptide and interrupting consequent synthesis of peptidoglycan chains. As a result, cefpodoxime inhibits bacterial septum and cell wall synthesis formation.NCI
code
  • C65305
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