About: Cefuroxime Sodium     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Cefuroxime Sodium
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Cefuroxime Sodium
UMLS_CUI
  • C0701852
CAS_Registry
  • 56238-63-2
FDA_UNII_Code
  • R8A7M9MY61
Contributing_Source
  • FDA
Chemical_Formula
  • C16H15N4O8S.Na
Legacy_Concept_Name
  • Cefuroxime_Sodium
FULL_SYN
  • 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, 3-(((aminocarbonyl)oxy)methyl)-7-((2-furanyl(methoxyimino)acetyl)amino)-8-oxo-, Monosodium Salt(6R-(6alpha,7beta(Z)))-SNNCI
  • Cefuroxime SodiumPTNCI
  • CEFUROXIME SODIUMPTFDAR8A7M9MY61
  • ZinacefBRNCI
  • CefuroxSYNCI
  • KefuroxBRNCI
  • LifuroxSYNCI
DEFINITION
  • The sodium salt form of cefuroxime and a semi-synthetic, broad-spectrum, beta-lactamase resistant, second-generation cephalosporin antibiotic with bactericidal activity. Cefuroxime sodium inhibits bacterial cell wall synthesis by inactivating penicillin binding proteins (PBPs) thereby interfering with the final transpeptidation step required for cross-linking of peptidoglycan units which are a component of the cell wall. Lack of cross-linking results in a reduction of cell wall stability and leads to cell lysis.NCI
code
  • C47439
sameAs
is Has_Salt_Form of
is sameAs of
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