About: Establishing of the Biotechnology Institute ASCR

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rdf:type	http://linked.opendata.cz/ontology/domain/vavai/Zamer
Description	The goal is to lay foundations for a new Biotechnology Institute Acad.Sci. CR (BTI). BTI will deal with biotech applied research, collaborate with relevant commercial subjects and be a source of new spin-off companies. In 2007, %22modest%22 foundations of BTI will exist as a Biotechnology Section of IMG (in an existing buiding for 60 people), in 2008 it will become independent. In 2007-2009 a new BTI building for ca 200 employees will be built (funded mainly from EU structural funds) and become fully operational in 2010-2011, with 15 research groups. The main research areas will be: diagnostics for reproductive medicine; recombinant antigens, vaccines, antibodies, and other diagnostic and therapeutics agents; development of advanced analytical and preparative methods for practical biotechnology applications; applied chemical genetics; transgenic animals. BTI will be financed by a combination of institutional core support, other public sources and collaborations with the private sector. (en) Hlavním cílem je vybudovat základy nového samostatného Biotechnologického ústavu AVČR (BTÚ AVČR), jehož primární náplní bude soustředěný biotechnologicky orientovaný aplikovaný výzkum a vývoj, v úzké spolupráci s realizačními subjekty. Základním věcným záměrem je docílit mezinárodně výrazných a ekonomicky významných aplikačních výsledků, a to předevších v následujících tematikách: diagnostika pro reprodukční medicínu; vývoj rekombinantních antigenů, vakcín, protilátek a dalších diagnostik a terapeutik; vývoj pokročilých analytických a preparativních metod pro praktické biotechnologické aplikace; aplikovaná chemická genetika; příprava transgenních zvířat.
Title	Establishing of the Biotechnology Institute ASCR (en) Vybudování Biotechnologického ústavu AV ČR
http://linked.open...kovaStatniPodpora	http://linked.opendata.cz/resource/domain/vavai/zamer/AV0Z50520701/celkovaStatniPodpora
http://linked.open...ez/celkoveNaklady	http://linked.opendata.cz/resource/domain/vavai/zamer/AV0Z50520701/celkoveNaklady
http://linked.open...datumDodatniDoRIV	2014-06-17 (xsd:date)
http://linked.open...vavai/cez/dodavka	http://linked.opendata.cz/resource/domain/vavai/dodavka/CEZ14-AV0-U%2F01%3A1
http://linked.open...ez/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...in/vavai/cez/faze	33175401
http://linked.open...ai/cez/hlavniObor	EI - Biotechnologie a bionika
http://linked.open...vai/cez/hodnoceni	U - Uspěl podle zadání, tj. byly splněny cíle a jeho předpokládané výsledky uvedené ve smlouvě / rozhodnutí o poskytnutí podpory
http://linked.open.../cez/kategorieVaV	NV - Aplikovaný výzkum s výjimkou průmyslového výzkumu (tzv. %22neprůmyslový výzkum%22)
http://linked.open.../cez/klicovaSlova	Biotechnology Institute; diagnostics; reproduction medicine; recombinant proteins; monoclonal antibodies; chemical genetics; transgenic animals; moleular therapeutics; autoimmune diseases; gene expression profiling; quantitative PCR; vaccines (en)
http://linked.open...cez/partnerHlavni	Biotechnologický ústav AV ČR, v. v. i.
http://linked.open...z/poceVysledkuRIV	309 (xsd:int)
http://linked.open...inujicichPrijemcu	0 (xsd:int)
http://linked.open...cez/pocetPrijemcu	1 (xsd:int)
http://linked.open...ocetSpoluPrijemcu	0 (xsd:int)
http://linked.open...enychVysledkuVRIV	309 (xsd:int)
http://linked.open...lneniVMinulemRoce	2013-11-29 (xsd:date)
http://linked.open.../prideleniPodpory	http://linked.opendata.cz/resource/domain/vavai/cez/prideleniPodpory/AV0Z50520701
http://linked.open.../vavai/cez/resort	Academy of Sciences of the Czech Republic
http://linked.open...iciPoslednihoRoku	2013
http://linked.open...atUdajeProjZameru	2014
http://linked.open...usZobrazovaneFaze	DUU
http://linked.open...ez/ukonceniReseni	2013-12-31 (xsd:date)
http://linked.open.../cez/vedlejsiObor	EB - Genetika a molekulární biologie
http://linked.open...ez/zahajeniReseni	2007-01-01 (xsd:date)
http://linked.open...n/vavai/cez/zamer	Z - Výzkumný záměr financovaný ze státního rozpočtu
http://linked.open...sledkuDodavatelem	Výzkumný záměr umožnil vybudovat stabilní a rozvíjející se ústav nasměrovaný na výzkum v oblasti molekulárně biologických věd a převod biotechnologických metod a molekulárních nástrojů k diagnostice a léčbě patologického stavu buňky do humánní a verinární medicíny, umožnil kontinuální nárůst publikací v kvalitních mezinárodních časopisech a nárůst výsledků využitelných v praktických aplikacích. (cs) RP enabled establishment of a more stable and growing Institute focused on basic research in molecular biology with transfer of biotechnological methods and tools to human and veterinary medicine, allowing continued growth of publications in high-quality international journals and increasing results applicable in pracise. (en)
http://linked.open...cez/zivotniCyklus	ZBBBBBKU
is http://linked.open...n/vavai/riv/zamer of	Partial deficiency of HIF-1 alpha stimulates pathological cardiac changes in streptozotocin-induced diabetic mice The effect of tetrabromobisphenol A on protamine content and DNA integrity in mouse spermatozoa Effect of zearalenone on reproductive parameters and expression of selected testicular genes in mice VDAC2 and aldolase A identified as membrane proteins of K562 cells with increased expression under iron deprivation Towards a better understanding of the specificity of protein-protein interaction Transgenic mouse model expressing tdTomato under involucrin promoter as a tool for analysis of epidermal differentiation and wound healing Ubiquitin-activating enzyme (UBA1) is required for sperm capacitation, acrosomal exocytosis and sperm-egg coat penetration during porcine fertilization 3 days Experimental design and statistical data analysis for qPCR 3 days Hands-on qPCR 1 day Sample preparation and quality control of nucleic acids The added value of single-cell gene expression profiling Association of obesity susceptibility gene variants with metabolic syndrome and related traits in 1,443 czech adolescents Automatic workflow for the classification of local DNA conformations Assignment of DNA conformers, web server dnas.img.cas.cz Effect of tetrabrombisphenol A on induction of apoptosis in the testes and changes in expression of selected testicular genes in CD1 mice Multiplexed immunoassays for simultaneous quantification of cardiovascular biomarkers in the model of HG-nitro-L-arginine methylester (L-name) hypertensive rat Plasticity Response in the Contralesional Hemisphere after Subtle Neurotrauma: Gene Expression Profiling after Partial Deafferentation of the Hippocampus Single blastomere expression profiling of Xenopus laevis embryos of 8 to 32-cells reveals developmental asymmetry RT-qPCR work-flow for single-cell data analysis Another role of proline: stabilization interactions in proteins and protein complexes concerning proline and tryptophane Intracellular expression profiles measured by real-time PCR tomography in the Xenopus laevis oocyte Localization of porcine seminal plasma (PSP) proteins in the boar reproductive tract and spermatozoa MMP19 is essential for T cell development and T cell-mediated cutaneous immune responses alpha-Lipoic acid modulates extracellular matrix and angiogenesis gene expression in non-healing wounds treated with hyperbaric oxygen therapy Profiling tumor-associated markers for early detection of malignant mesothelioma: an epidemiologic study The influence of fluorides on mouse sperm capacitation Analysis of in vitro and in vivo characteristics of human embryonic stem cell-derived neural precursors Characterization of Lymphocyte Subsets in Patients with common variable immunodeficiency reveals subsets of naive human B cells marked by CD24 expression Ice-age endurance: the effects of cryopreservation on proteins of sperm of common carp, Cyprinus carpio L Anticancer Drugs Targeting the Mitochondrial Electron Transport Chain Asbestos exposure affects poly(ADP-ribose) polymerase-1 activity: role in asbestos-induced carcinogenesis Association of MiR-126 with Soluble Mesothelin-Related Peptides, a Marker for Malignant Mesothelioma Electrophoretic and zymographic characterization of proteins isolated by various extraction methods from ejaculated and capacitated boar sperms The influence of a subanaesthetic dose of ketamine on circulating pro-inflammatory cytokines and serotonin in brain reply Inhibitors of Succinate: Quinone Reductase/Complex II Regulate Production of Mitochondrial Reactive Oxygen Species and Protect Normal Cells from Ischemic Damage but Induce Specific Cancer Cell Death Native Red Electrophoresis - A new method suitable for separation of native proteins Primer Sequence Disclosure: A Clarification of the MIQE Guidelines The Potential Role of CD133 in Immune Surveillance and Apoptosis: A Mitochondrial Connection? Preconceptional paternal glycidamide exposure affects embryonic gene expression: Single embryo gene expression study following in vitro fertilization Preanalytics and standardization session. New applications and technologies. Reproductive tissue expression and sperm localization of porcine beta-microseminoprotein Structure of the mouse galectin-4 N-terminal carbohydrate-recognition domain reveals the mechanism of oligosaccharide recognition Towards the standardization of the preanalytical phase. Introduction to Real-Time qPCR XVIIth Symposium of Czech Reproductive Immunologist with international participation Adverse effect of tetracycline and doxycycline on reproductive tract development of CD1 mice alpha-Tocopheryloxyacetic acid is superior to alpha-tocopheryl succinate in suppressing HER2-high breast carcinomas due to its higher stability Alpha-Tocopheryl Succinate Inhibits Autophagic Survival of Prostate Cancer Cells Induced by Vitamin K3 and Ascorbate to Trigger Cell Death Adverse effect of tetracycline and doxycycline on testicular tissue and sperm parameters in CD1 outbred mice Targeting the Mitochondrial Electron Transport Chain Complexes for the Induction of Apoptosis and Cancer Treatment TATAA courses : 3 days Hands-on qPCR TATAA courses – 2 days Hands-on qPCR TATAA courses – 1 day Sample preparation and quality control of nucleic acids TATAA courses – 2 days Experimental design and statistical data analysis for qPCR TATAA courses – 2 days Experimental design and statistical data analysis for qPCR TATAA courses – 2 days Hands-on qPCR TATAA courses – 1 day Sample preparation and quality control of nucleic acids TATAA courses – 2 days Experimental design and statistical data analysis for qPCR TATAA courses – 2 days Experimental design and statistical data analysis for qPCR 3 days Hands-on qPCR XIXth Symposium of immunology and Biology of Reproduction with international participation 2 days Hands-on qPCR 1 day Sample preparation and quality control of nucleic acids Efficacy of S-adenosylhomocysteine hydrolase inhibitors, D-eritadenine and (S)-DHPA, against the growth of Cryptosporidium parvum in vitro TATAA qPCR course TATAA qPCR course TATAA qPCR course

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