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About: Departmental Programme of Research and Development - MH II from 2008 to 2011 Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/resource/domain/vavai/Aktivita, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	http://linked.opendata.cz/resource/domain/vavai/Aktivita
Title	Resortní program výzkumu a vývoje – MZ II na léta 2008 - 2011 (cs) Departmental Programme of Research and Development - MH II from 2008 to 2011 (en)
skos:notation	NS
http://linked.open...cea/pgm/FINCSTCEL	1737169
http://linked.open...ai/cea/pgm/XD_PGM	1099729112
http://linked.open...a/pgm/cilAktivity	Vypracovat nové diagnostické metody – zejména genetické postupy – sloužící k co nejrychlejšímu a nejpřesnějšímu rozpoznání chorob, získat nové poznatky o patogenezi chorob nutné pro zajištění vysoce efektivní léčby, analyzovat jednotlivé parametry léčebné péče tak, aby byly vytvořeny předpoklady pro kvantifikaci hodnocení kvality a analýzu poměru cost/benefit ve zdravotnictví, získat údaje umožňující průběžné hodnocení vývoje zdravotního stavu populace a jeho srovnávání se stavem v ostatních státech Evropské unie. (cs) To elaborate new diagnostic methods, especially genetic methods, which lead to the fastest and the most exact way of diagnosis; to get new knowledge in pathogenesis of diseases necessary for guarantee of high efficient treatment; to analyse particular characteristics of medical care so that the conditions of quality assessment and the analysis of the cost/benefit rate in health service could be created; to get data which continuosly compound the evolution of health state of population and its comparison with other countries of European Union. (en)
http://linked.open...isloUsneseniVlady	1388
http://linked.open...umSchvaleniVladou	2007-12-12 (xsd:date)
http://linked.open...a/pgm/rokUkonceni	2011
http://linked.open...a/pgm/rokZahajeni	2008
http://linked.open...a/pgm/typAktivity	P - Program
http://linked.open...inostNotifikaceEK	J - Program nepodléhá oznámení (notifikaci) Evropské komisi z jiného důvodu
http://linked.open...ai/cea/pgm/resort	Ministry of Health
is http://linked.open...avai/cep/aktivita of	Individual 5-fluorouracil dose individualization in patients with colorectal cancer Use of New Molecular Genetic Methods for the Early Detection of Disease Progression in Patients with Resectable, Primary Colorectal Carcinoma Based On Circulating Tumor Cells and Free Tumor Nucleic Acids. Effect of Hemodialysis and Renal Transplantation on Reproduction Function in Men with Chronic Renal Insufficiency Study of the mechanism of neoadjuvant chemotherapy-induced cell death and mechanism of chemotherapy resistance in patient with breast carcinoma Influence of biocompatible coated heart lung machine tubing set on fibrinogen function, assessed by the TEG Functional Fibrinogen Mechanisms and consequences of the accumulation of lipids in liver associated with metabolic syndrome - the possibilities of nutritional and pharmacological intervention Childhood obesity surveillance in the Czech Republic Cost effectiveness of diagnostic and therapy in endocrine and metabolic diseases Metal intolerance as a risk factor in implantology - a consecutive study. Terlipressin in the treatment of catecholamine-resistant septic shock Urological and endocrinological factors of hormonal substitution therapy in patients with Kallmann syndrome Surgical Prevention of the Breast Cancer in Patients with Hereditary Disposition Screening of mutations in the duplicated region of the PKD1 gene from families with autosomal dominant polycystic kidney disease Acute Stroke Study of Optimized tPA Dosing in Correlation with Artery Status Disection of mechanism behind chromosomal aberation cumulation during long term cultivation of human embryonic stem cells. The role of p73 protein isoforms in medulloblastoma pathogenesis: an immunocytochemical and microarray study Neoadjuvant chemoterapy in brest carcinoma Spinocerebellar Ataxias - The Extension of Molecular Methods with Onwards Longitudinal Multidisciplinary Study of Patients´ Families Mortality and health status of former injection drug users using low threshold services in 1994 - follow-up study. Association of polymorphisms in genes for matrix metalloproteinases, their inhibitors, ACE and ACE2 with central pulse pressure in cardiovascular patients The role of chromosome 1 abnormalities and NF-kappaB cascade in patogenesis of multiple myeloma Respiration, oxidative stress and mitochondrial morphology of Langerhans islets suited for transplantation Evaluation and development of new perspective antimycobacterial drugs and prodrugs active against multidrug resistant strains The role of serotonin and noradrenaline reuptake inhibitors as potential antidotes for intoxications with dangerous synthetic drugs 2C-B and DOB – pharmacokinetics, behavioral and QEEG effects Role of metabotropic mGlu2/3 a AMPA glutamatergic receptors in neurobiology of schizophrenia Aditive effects of omega-3 polyunsaturated fatty acids and pioglitazone in the treatment of type 2 diabetes mellitus Prospective Randomized Study Comparing the Effectiveness and Safety of Transobturatory Tension-Free Vaginal Tape (TVT-O) and Minitape (TVT-S) Provision of culturally differentiated nursing care in selected minorities in the Czech Republic The presence of sortase enzymes SrtB, SrtC and SrtD in clinical isolates of Streptocococcus pneumoniae and their role in the virulence and resistance to antimicrobials. Molecular typing of bacteriocins produced by strains of Escherichia coli isolated from clinical material: identification of colicin and microcin types among commensal and pathogenic strains Proteomic analysis of the wall of the abdominal aortic aneurysm (AAA), comparing to atherosclerotic and healthy aortas Mnagment of care of patients with acute heart failure, their min-term prognosis and multivariate prognostic model. The role of oxidative stress and genetic factors on the progress of liver impairment in patients with Wilson disease. Expression of genes and proteins playing a role in the human reproduction - damage biomarkers Optimizing Volume Resuscitation in Severely Burnt Adult Patients by Means of Minimally Invasive Hemodynamic Monitoring and Minimazing Blood Loss during Operations by Bedside Hemostasis Monitoring Using the Thromboelastograph Analyzer Improving the quality of drug prescribing in senior population - validation of instruments for drug policy use in the Czech Republic Regeneration of liver parenchyma of the patients suffering from metastasizing colorectal carcinoma stimulated by embolization of a portal vein branch and autologous haemopoietic progenitor cells. Investigation of pathophysiology of human leukemias/lymphomas during manipulation of oncogenic microRNAs. Monocyte subpopulations in kidney transplantation and regulatory mechanisms of human macrophage differentiation Investigation of cerebrospinal fluid in diagnostics of inborn errors of neurotransmitter metabolism and mitochondrial diseases. Genetic bases of cytochrome c oxidase deficiency The Position of Ambulatory 24-Hour Dual-Probe pH-Metry in the Diagnostics of Extraesophageal Reflux Optimalization of Clinical Information Acquisition from Medical Registries Changes in global and regional parameters of myocardial contractility in patients after heart transplantation. Development of experimental vaccine against WT 1 for immunotherapy of tumors Biofilm - important virulence factor of infections of urinary catheters; how to detect and suppress it The Role of Cytokines and Growth Factors in Liver Regeneration or Tumor Progression after Portal Vein Embolization in Patients with Colorectal Liver Metastases. Influence of neoadjuvant biological therapy upon regeneration of liver parenchyma after surgical treatment -porcine experimental model Distribution of iodine in human organism Optimized dendritic cells loaded with universal tumor antigens as a potent individualized cancer vaccine Mechanisms of immunoresistance in glioblastoma Assessment of extent and composition of atherosclerotic plaques in coronary arteries based on ultrasonographic investigation of carotid arteries and polymorphisms of specific genes Assesment of perioperative prognostic factors of breast cancer disease Persistent prefrontal activation as an marker of craving and predictor of loss of persistence during the treatment of addiction Dyslipidemia and prehypertension - association of dyslipidemic phenotypes with prevalence of prehypertension. Association of prehypertension with markers of insulin resistance, inflammation, endothelial dysfunction and subclinical atherosclerosis. Epidemiologic study of genetic and behavioral risk factors in kidney cancer Assessment of free light chains as auxiliary marker for the evaluation of prognosis and of the response to treatment in patients with multiple myeloma and with monoclonal gammopathy of unknown significance Analysis of changes in genome and its expression in chronic lymphocytic leukemia patients during the disease development Monitoring of voriconazole plasma levels Importance of non-culture methods for diagnostics of invasive fungal infections caused by filamentous fungi from bronchoalveolar lavage fluid in hematooncological patients Muscle metabolism after renal transplantation: early exercise intervention, selective nutrition and gene polymorphism Analysis of the BSCL 2 gene and a clinical study among Czech patients with hereditary motor neuropathy. Chronic myeloid leukemia : immunological studies with mouse and human cells transformed by the bcr-abl fusion gene Influence of rheopheresis therapy on retinal function in age-related macular degeneration Neuroactive steroids in diagnostics of postpartum mental disorders Gene polymorphisms and intrarenal expression of genes in Focal segmental glomerulosclerosis and their relation to progression of the disease The influence of temperature on thrombelastography measurement results PAR´s, chemokines and their receptors´ expression changes in pulmonary fibrosing processes and in pulmonary processes with alveolar number reduction without scaring (IPF vs. COPD) The effect of ectopic fat accumulation and chronic inflammation on the development of liver injury and disorders associated with insulin resistance. The effect of reproduction age on the sensitiveness of vascular wall to external, metabolic and genetic cardiovascular risk factors, longitudinal population study Health risks from occupational and environmental radon exposure Nurse integration into the community care of the health care system of the Czech Republic and comparison with situation in EU countries Health risks of local skin toxicity determined by alternative toxicological methods in vitro The role of increased epoxyeicosatrienoic acids level in the regulation of renal function and pathophysiology of renovascular hypertension Novel approach to blood pressure control and organ protection- intervention to renin-angiotensin and endothelin systems The role of probiotics and dental plaque bacteria in development of atheroscklerotic changes in clinical praxis and experimental model Genetic factors influencing the progression of selected forms of nephrotic syndrome Elaboration of guidelines for assessment of growth of a breastfed child pursuant to a comparison of growth of exclusively breastfed children with both, current Czech growth charts and the standards of the World Health Organisation. The role of chronic infection in etiopathogenesis of prostate carcinoma Intranasal vaccination in prevention of autoimmune diseases Innovation of treatment of critically burned patients by covering largely meshed autografts with human keratinocytes cultured in vitro on acellular xenomatrix Effect of surgical management on development of lung function and formation of skeletal deformity in children with congenital diaphragmatic hernia. Predictive value of adipokines in rheuamtoid arthritis Complement in the pathogenesis of autoimmune thyroid disorders Nutrigenomic interacttions in different weight reducing diets. Relation to fatty acid composition.

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