About: Implementation of molecular biological methods in diagnostics and treatment

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An Entity of Type : http://linked.opendata.cz/resource/domain/vavai/Aktivita, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	http://linked.opendata.cz/resource/domain/vavai/Aktivita
Title	Implementace molekulárně-biologických metod v diagnostice a léčbě (cs) Implementation of molecular biological methods in diagnostics and treatment (en)
skos:notation	NM
http://linked.open...ai/cea/pgm/XD_PGM	250
http://linked.open...a/pgm/cilAktivity	Fast transfer of the latest theoretical knowledge of mollecular biology into the diagnostical and curative practice, increase of the competitiveness of Czech medicine. Increase of the efficiency of Czech medical research and the increase of the share of its contribution into the science on the world-wide scale. (en) Rychlé převedení nejnovějších teoretických poznatků molekulární biologie do diagnostické a léčebné praxe, zvýšení konkurenceschopnosti české mediciny. Zvýšení efektivity české lékařského výzkumu a zvýšení podílu jeho příspěvku lékařské vědě v mezinárodním měřítku. (cs)
http://linked.open...a/pgm/rokUkonceni	2005
http://linked.open...a/pgm/rokZahajeni	1998
http://linked.open...a/pgm/typAktivity	P - Program
http://linked.open...ai/cea/pgm/resort	Ministry of Health
is http://linked.open...avai/cep/aktivita of	Clinical application of molecular diagnostic approaches of gene rearrangements in malignant tumors in childhood Charcot - Marie - Tooth 1 and HNPP - investigation in pacients and families using DNA microsatellite STR markers from region 17p.11.2 - p12. Inborn skeletal disorders caused by mutations in fibroblast growth factor receptors/FGFR/ The role of nuclear hormone receptors in regulation of differentiation of cancer cells. The role of TGF-betal and CD14 gene polymorphisms in chronic kidney allograft rejection and progression of chronic glomerulonephritis Complication of pregnancy associated with hyperhomocysteinemia: the role of genetic variants in the development of neural tube defects, orofacial clefts, and preeclampsia Molecular mechanism of hemoglobulin disorders in the Czech Republic Detection of origin of infection after extensive surgical treatment Electrophysiologic and genetic aspects of tinnitus ROLE OF CANALICULAR MEMBRANE TRANSPORTERS IN CHOLESTATIC LIVER DISEASES Expression of ob gene and coding leptin production in hepatocytes of liver with steatossis. Spinocerebellar ataxis - complex diagnostics with applicationof molecular methods and longitudinal multidisciplinar study of patients' families. Atherosclerotic changes and DNA adducts External quality control in DNA laboratories Molecular diagnostic and prognosis in acute myeloid leukemia Biomarkers for optimization of the treatment of soft - tissue sarcomas The use interphase FISH for the determination of individuals with elevated risk of the induction of hemoblastoses The role of CBP in anti-leukemic processes Analysis of telomerase activity in benign and malignant breast lesions Cooperation of E-cadherin and cell surface carbohydrates in intercellular adhesivity Improved diagnosis of muscular dystrophies using methods for identification of DGC proteins. Multiple drug resistance of leukemia cells and its determination in vitro The role of selectin-mediated adhesion in allograft rejection:a novel study in mice with defective selectin ligand expression Mild hyperhomocysteinemia in the Czech population: analysis of genetic factors among patients with atherosclerosis. Familial juvenile gouty nefropathy : gene mapping and identification. Genetic regulation of IgE expression - implications for human atopic diseases DNA chip technology for high-throughput mutation analysis and differential gene expression studies. Establishment of methodological prerequisites for gene therapy of graft-versus-host disease Diferental gene expression analysis in oncohematological diseases. Analysis of molecular basis of red cell antigens with respect to prenatal diagnostic of haemolytic disease of the newborn and to solving of transfusion-related problems The usage of FISH metods (LSI and MFISH)and echocardiography for the complex diagnostic systém of congenital heart diseases. Human ameloblastin Population,clinical and molecular genetic study of mutations linked to thrombophilia for an early prevention and treatment Detekce a charakterizace %22blank%22 alel HLA 1. třídy v české populaci. Význam pro transplantační medicínu BURKHOLDERIA CEPACIA infection in patients with cystic ficrosis in Czech Republic. Moleculary biology diagnostics and clinical application. Development of production technology of selected endoradiotherapeutical radiopharmaceuticals in a carrier-free form for subsequent clinical tests Genetic base of acute pain perception Spinocerebellar ataxias - the extension of molecular methods with onwards longitudinal multidisciplinary study of patients´families. Mutation analysis of connexin 26 gene as the most frequent cause of prelingual nonsyndromic hearing loss. The novel molecular biology methods in early diagnosis of acute and chronic rejection. Determination of gene expression within rejecting renal allografts. Mutational status of IgVH genes in chronic lymphocytic leukemia Implementation of high-performance liquid chromatography (HPLC) to the molecular testing of inherited haemostatic defects and to the histocompatibility tests for haematopoietic stem cell transplantation (HSCT). A functional assay for heterozygous mutations in the GTPase activating protein related domain of the neurofibromatosis type 1 gene Development of a method for prediction of pathological expansions of trinucleotide repeats in the human genome Non-specific and specific detection of bacterial colonization of total hip and knee prosthesis by PCR diagnostics: testing of statistical consistency Thrombotic thrombocytopenic purpura: molecular-biological diagnosis
is http://linked.open...avai/ves/aktivita of	SMZ02002NM SMZ02003NM SMZ0NM2000 SMZ0NM2001

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