About: Mutational status of IgVH genes in chronic lymphocytic leukemia     Goto   Sponge   NotDistinct   Permalink

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  • Introducing examination of the mutational status of IgVH genes will help the clinicians in therapeutic decision in patients with CLL. The results of the mutational status of IgVH genes and their prognostic significance will be correlated with other prognostic markers. (en)
  • Zavedení vyšetření mutačního stavu IgVH genů pomůže klinikům v procesu rozhodování o léčbě pacientů s CLL: Výsledky mutačního stavu IgVH genů a jejich prognostický dopad budou korelovány s jinými prognostickými ukazateli.
Title
  • Mutational status of IgVH genes in chronic lymphocytic leukemia (en)
  • Mutační stav IgVH genů u pacientů s chronickou lymfatickou leukemií
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  • NM7604
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  • chronic lymphocytic leukemia;immunoglobulin VH genes;prognostic factors;PCR;sequencing (en)
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  • Metodika stanovení mutačního stavu IgVh genů zavedena do prognostiky chronic.lymfatic. leukemie (CLL). Vyšetřeno 850 pacientů,analyzováno 885 alel IgVh. U 337 pac. měl mutační stav IgVh genů a klinické stádium dle Raie největší prognost.dopad na přežití. (cs)
  • Detection of mutation status IgVh genes introduced into prognostics of chronic lymphocytic leukemia (CLL).850 pts with CLL,885 IgVh alleles were analyzed.By 337 pts mutation status IgVh genes and Rai clinical stage had most pronounced effect on survival. (en)
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  • PCR
  • chronic lymphocytic leukemia
  • prognostic factors
  • immunoglobulin VH genes
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