About: Vascular Endothelial Growth Factor Receptor 3     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Vascular Endothelial Growth Factor Receptor 3
equivalentClass
OMIM_Number
  • 136352
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Receptor
Preferred_Name
  • Vascular Endothelial Growth Factor Receptor 3
UMLS_CUI
  • C0169539
Legacy_Concept_Name
  • FMS-Related_Tyrosine_Kinase-4
FULL_SYN
  • EC 2.7.10.1SYNCI
  • Vascular Endothelial Growth Factor Receptor 3PTNCI
  • AV3SYNCI
  • FMS-Like Tyrosine Kinase 4SYNCI
  • FLT4SYNCI
  • Tyrosine-Protein Kinase Receptor FLT4SYNCI
  • VEGFR3SYNCI
  • FMS-Related Tyrosine Kinase 4SYNCI
  • VEGFR-3SYNCI
Swiss_Prot
  • P35916
DEFINITION
  • Vascular endothelial growth factor receptor 3 (1363 aa, ~153 kDa) is encoded by the human FLT4 gene. This protein is involved in tyrosine phosphorylation, lymph vessel formation and ligand-dependent signaling.NCI
DesignNote
  • A type I membrane protein tyrosine kinase receptor for VEGF-C, vascular endothelial growth factor receptor 3, contains seven immunoglobulin-like C2-type domains. Vascular endothelial growth factors, working through VEGF receptor-3, promote angiogenesis and metastatic spread of cancer cells. (from Nat Med 2001. 7:151 & 186)
code
  • C26203
sameAs
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