About: Vatalanib     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Vatalanib
rdfs:subClassOf
Has_Salt_Form
Has_Target
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Vatalanib
NSC_Code
  • 719335
UMLS_CUI
  • C0912586
CAS_Registry
  • 212141-54-3
In_Clinical_Trial_For
  • VHL-related hemangioblastoma; refractory or recurrent metastatic colon or rectal cancer; unresectable malignant mesothelioma; primary or secondary myelodysplastic syndromes.
FDA_UNII_Code
  • 5DX9U76296
Contributing_Source
  • FDA
ALT_DEFINITION
  • A substance that is being studied in the treatment of cancer. It belongs to the families of drugs called protein tyrosine kinase inhibitors and VEGF receptor kinase inhibitors.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 43530
PDQ_Closed_Trial_Search_ID
  • 43530
Chemical_Formula
  • C20H15ClN4
Legacy_Concept_Name
  • PTK787
FULL_SYN
  • VATALANIBPTFDA5DX9U76296
  • PTK787/ZK 222584PTNCI-GLOSSCDR0000046711
  • N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamineSNNCI
  • ZK-232934CNNCI
  • CGP-79787CNNCI
  • VatalanibPTNCI
  • vatalanibPTNCI-GLOSSCDR0000390321
DEFINITION
  • An orally bioavailable anilinophthalazine with potential antineoplastic activity. Vatalanib binds to and inhibits the protein kinase domain of vascular endothelial growth factor receptors 1 and 2; both receptor tyrosine kinases are involved in angiogenesis. This agent also binds to and inhibits related receptor tyrosine kinases, including platelet-derived growth factor (PDGF) receptor, c-Kit, and c-Fms.NCI
code
  • C1868
http://linked.open...y/mesh/hasConcept
is someValuesFrom of
is Has_Free_Acid_Or_Base_Form of
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 116 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software