About: Bleomycin Antibiotic

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Bleomycin Antibiotic
rdfs:subClassOf	ANTINEOPLASTIC ANTIBIOTICS DNA Intercalating Agent
Semantic_Type	Chemical Viewed Functionally
Preferred_Name	Bleomycin Antibiotic
NCI_META_CUI	CL027277
Legacy_Concept_Name	Bleomycin_Antibiotic
CHEBI_ID	CHEBI:22907
FULL_SYN	Bleomycin AntibioticHDNCI BleomycinsSYNCI
DEFINITION	A basic glycopeptide antineoplastic antibiotic isolated from Streptomyces verticillus. Bleomycin antibiotics form complexes with iron that react with molecular oxygen to produce superoxide and hydroxyl free radicals, causing single- and double-stranded breaks in DNA. These reactive oxygen species also induce lipid peroxidation, carbohydrate oxidation, and alterations in prostaglandin synthesis and degradation.NCI
code	C2311
is rdfs:subClassOf of	Peplomycin Boanmycin Hydrochloride Pingyangmycin Peplomycin Sulfate Bleomycin A2 Bleomycin Sulfate BLEOMYCIN Bleomycin B2

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