About: Bleomycin A2

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Bleomycin A2
rdfs:subClassOf	Bleomycin Antibiotic
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Amino Acid, Peptide, or Protein Antibiotic
Preferred_Name	Bleomycin A2
NSC_Code	146842
UMLS_CUI	C0005736
CAS_Registry	11116-31-7
FDA_UNII_Code	13M89UEA7W
Contributing_Source	FDA
Chemical_Formula	C55H84N17O21S3
Legacy_Concept_Name	Bleomycin_A2
CHEBI_ID	CHEBI:3139
FULL_SYN	Bleomycin A2PTNCI N1-(3-(Dimethylsulfonio)propyl)bleomycinamideSNNCI Pingyangmycin A2SYNCI Zhengguangmycin A2SYNCI BLEOMYCIN A2PTFDA13M89UEA7W BLEOMYCIN A2SYDTPNSC0146842
DEFINITION	The primary bleomycin species in bleomycin sulfate, a mixture of the sulfate salts of several basic glycopeptide antineoplastic antibiotics isolated from Streptomyces verticillus. Bleomycin A2 forms complexes with iron that reduce molecular oxygen to superoxide and hydroxyl radicals which cause single- and double-stranded breaks in DNA; these reactive oxygen species also induce lipid peroxidation, carbohydrate oxidation, and alterations in prostaglandin synthesis and degradation. (NCI04)NCI
code	C311
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0002654

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