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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Bleomycin
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Antibiotic
  • Organic Chemical
Preferred_Name
  • Bleomycin
NSC_Code
  • 125066
UMLS_CUI
  • C0005740
CAS_Registry
  • 11056-06-7
FDA_UNII_Code
  • 40S1VHN69B
Contributing_Source
  • FDA
ALT_DEFINITION
  • The active ingredient in a drug that is used to treat many types of cancer and is being studied in the treatment of other types of cancer. It comes from the bacterium Streptomyces verticillus. Bleomycin damages DNA and may kill rapidly growing cancer cells. It is a type of antineoplastic antibiotic.NCI-GLOSS
Legacy_Concept_Name
  • Bleomycin
CHEBI_ID
  • CHEBI:3139
FULL_SYN
  • BleoSYDTPNSC0125066
  • BLMABNCI
  • BLEOABNCI
  • BLEOMYCINPTFDA40S1VHN69B
  • BleomycinPTNCI
  • bleomycinPTNCI-GLOSSCDR0000045169
  • BleomycinSYNCITCGA
DEFINITION
  • A mixture of glycopeptide antineoplastic antibiotics isolated from the bacterium Streptomyces verticillus. Bleomycin forms complexes with iron that reduce molecular oxygen to superoxide and hydroxyl radicals which cause single- and double-stranded breaks in DNA; these reactive oxygen species also induce lipid peroxidation, carbohydrate oxidation, and alterations in prostaglandin synthesis and degradation.NCI
code
  • C313
sameAs
http://linked.open...y/mesh/hasConcept
is someValuesFrom of
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