About: Bleomycin B2     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Bleomycin B2
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Bleomycin B2
UMLS_CUI
  • C0005738
CAS_Registry
  • 9060-10-0
FDA_UNII_Code
  • M62KK37O40
Contributing_Source
  • FDA
Chemical_Formula
  • C55H84N20O21S2
Legacy_Concept_Name
  • Bleomycin_B2
CHEBI_ID
  • CHEBI:28641
FULL_SYN
  • Bleomycin B2PTNCI
  • Bleomycinamide, N1-(4-((aminoiminomethyl)amino)butyl)-SNNCI
  • Phleomycin D2SYNCI
  • Dehydrophleomycin D1SYNCI
  • N1-(4-((Aminoiminomethyl)amino)butyl)bleomycinamideSNNCI
  • BLEOMYCIN B2PTFDAM62KK37O40
DEFINITION
  • One of the primary bleomycin species in bleomycin sulfate, a mixture of the sulfate salts of glycopeptide bleomycin A2 and B2 isolated from Streptomyces verticillus with potential antineoplastic activity. Bleomycin B2 forms complexes with iron that reduce molecular oxygen to superoxide and hydroxyl radicals which cause single- and double-stranded breaks in DNA; these reactive oxygen species also induce lipid peroxidation, carbohydrate oxidation, and alterations in prostaglandin synthesis and degradation.NCI
code
  • C81672
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