About: Core/Shell Nanofibers with Embedded Liposomes as a Drug Delivery System

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	We produced 2 different nanofiber-liposome systems in the present study: liposomes blended within nanofibers and core/shell nanofibers with embedded liposomes. We demonstrate that blend electrospinning does not conserve intact liposomes in contrast to coaxial electrospinning which enables the incorporation of liposomes into nanofibers. We report polyvinyl alcohol-core/poly-ε-caprolactone-shell nanofibers with embedded liposomes and show that they preserve the enzymatic activity of encapsulated horseradish peroxidase. The potential of this system was also demonstrated by the enhancement of mesenchymal stem cell proliferation. We produced 2 different nanofiber-liposome systems in the present study: liposomes blended within nanofibers and core/shell nanofibers with embedded liposomes. We demonstrate that blend electrospinning does not conserve intact liposomes in contrast to coaxial electrospinning which enables the incorporation of liposomes into nanofibers. We report polyvinyl alcohol-core/poly-ε-caprolactone-shell nanofibers with embedded liposomes and show that they preserve the enzymatic activity of encapsulated horseradish peroxidase. The potential of this system was also demonstrated by the enhancement of mesenchymal stem cell proliferation. (en)
Title	Core/Shell Nanofibers with Embedded Liposomes as a Drug Delivery System Core/Shell Nanofibers with Embedded Liposomes as a Drug Delivery System (en)
skos:prefLabel	Core/Shell Nanofibers with Embedded Liposomes as a Drug Delivery System Core/Shell Nanofibers with Embedded Liposomes as a Drug Delivery System (en)
skos:notation	RIV/68378041:_____/12:00377767!RIV13-AV0-68378041
http://linked.open...avai/predkladatel	Ústav experimentální medicíny Akademie věd České republiky, v. v. i.
http://linked.open...avai/riv/aktivita	I P S Z
http://linked.open...avai/riv/aktivity	I, P(1M0510), P(2B06130), P(GA202/09/1151), P(GAP304/10/1307), P(IAA500390702), P(NT12156), S, Z(AV0Z50200510), Z(AV0Z50390512), Z(AV0Z50390703), Z(AV0Z60220518), Z(MSM0021620849)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Rampichová, Michala Amler, Evžen Filová, Eva Míčková, Andrea Buzgo, Matej
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav experimentální medicíny AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	128801
http://linked.open...ai/riv/idVysledku	RIV/68378041:_____/12:00377767
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	tissue Engineering applications; electrospun nanofibers; liposomes (en)
http://linked.open.../riv/klicoveSlovo	liposomes electrospun nanofibers tissue Engineering applications
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[A53C784BFCD7]
http://linked.open...i/riv/nazevZdroje	Biomacromolecules
http://linked.open...in/vavai/riv/obor	FP
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	9 (xsd:int)
http://linked.open...vavai/riv/projekt	Novel scaffolds for osteochondral regeneration based on core/shell nanofibers enriched with a drug delivery system Centre for cardiovascular research Synthesis of new biomaterials and preparation of stem cell derived cells, and their aplications in for the treatment of diseases affecting human tissues derived from mesoderm: cartilage, bone, ligament and meniscus. Focused tandem shock waves and their potential application in cancer treatment and controlled drug delivery Smart nanofiber/liposme composite scaffold for bone regeneration Scaffolds from liposome nanofibers for tissue engineering
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	13
http://linked.open...iv/tvurceVysledku	Benada, Oldřich Filová, Eva Amler, Evžen Míčková, Andrea Rampichová, Michala Buzgo, Matej Lukáš, D. Fišar, Z. Tesařová, Martina
http://linked.open...ain/vavai/riv/wos	000303076200002
http://linked.open...n/vavai/riv/zamer	Microorganisms in Research and Biotechnology Molekulární, buněčné a systémové mechanizmy závažných onemocnění lidského organizmu, jejich diagnostika, terapie a farmakoterapie New biotechnologies, nanomaterials and stem cells for use in regenerative medicine Parazitismus a parazito-hostitelské vztahy na organismální, buněčné a molekulové úrovni Neuropsychiatrické aspekty neurodegenerativních onemocnění
issn	1525-7797
number of pages	11 (xsd:int)
http://bibframe.org/vocab/doi	10.1021/bm2018118
is http://linked.open...avai/riv/vysledek of	Core/Shell Nanofibers with Embedded Liposomes as a Drug Delivery System

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