About: Bleomycin Antibiotic     Goto   Sponge   Distinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Bleomycin Antibiotic
rdfs:subClassOf
Semantic_Type
  • Chemical Viewed Functionally
Preferred_Name
  • Bleomycin Antibiotic
NCI_META_CUI
  • CL027277
Legacy_Concept_Name
  • Bleomycin_Antibiotic
CHEBI_ID
  • CHEBI:22907
FULL_SYN
  • Bleomycin AntibioticHDNCI
  • BleomycinsSYNCI
DEFINITION
  • A basic glycopeptide antineoplastic antibiotic isolated from Streptomyces verticillus. Bleomycin antibiotics form complexes with iron that react with molecular oxygen to produce superoxide and hydroxyl free radicals, causing single- and double-stranded breaks in DNA. These reactive oxygen species also induce lipid peroxidation, carbohydrate oxidation, and alterations in prostaglandin synthesis and degradation.NCI
code
  • C2311
is rdfs:subClassOf of
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