About: Quinolone Antibiotic

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Attributes	Values
rdf:type	Class
rdfs:label	Quinolone Antibiotic
rdfs:subClassOf	Antibiotic
Semantic_Type	Chemical Viewed Functionally
Preferred_Name	Quinolone Antibiotic
UMLS_CUI	C1882518
ALT_DEFINITION	A group of derivatives of naphthyridine carboxylic acid, quinoline carboxylic acid, or NALIDIXIC ACID.MSH2002_06_01
Legacy_Concept_Name	Quinolone_Antibiotic
FULL_SYN	Quinolone AntibioticPTNCI
DEFINITION	The basic structure of quinolone is nalidixic acid that has limited therapeutic value. However, the development of fluorinated quinolones led to new derivative compounds with broad antibacterial activity. Both DNA gyrase and topoisomerase IV are targets of quinolones.NCI
code	C795
is rdfs:subClassOf of	LEVOFLOXACIN MOXIFLOXACIN HCL LOMEFLOXACIN HYDROCHLORIDE NORFLOXACIN LOMEFLOXACIN SPARFLOXACIN TROVAFLOXACIN MESYLATE MOXIFLOXACIN Irloxacin Piromidic Acid TROVAFLOXACIN Rufloxacin Sarafloxacin Hydrochloride TEMAFLOXACIN HYDROCHLORIDE Tilbroquinol Rosoxacin Tosufloxacin Monohydrate Tosufloxacin Tosylate Norfloxacin Succinil Sitafloxacin Sitafloxacin Anhydrous Tioxacin Marbofloxacin Nalidixate Sodium Tosufloxacin Zabofloxacin Levonadifloxacin Merafloxacin Sarafloxacin TEMAFLOXACIN Vosaroxin Gatifloxacin CIPROFLOXACIN Gemifloxacin Mesylate NALIDIXIC ACID CIPROFLOXACIN HYDROCHLORIDE GEMIFLOXACIN ALATROFLOXACIN MESYLATE CINOXACIN Difloxacin Droxacin Droxacin Sodium ENOXACIN Esafloxacin Fandofloxacin Garenoxacin Garenoxacin Mesylate GREPAFLOXACIN GREPAFLOXACIN HYDROCHLORIDE Pazufloxacin Pipemidic Acid Premafloxacin OFLOXACIN Balofloxacin Binfloxacin Danofloxacin Mesylate Nitroxoline Orbifloxacin Pradofloxacin Prulifloxacin Geroquinol Fleroxacin Enrofloxacin Ecenofloxacin Amifloxacin Amifloxacin Mesylate Danofloxacin Difloxacin Hydrochloride Pefloxacin Pefloxacin Mesylate Clinafloxacin Besifloxacin Hydrochloride Cadrofloxacin Cetefloxacin Lomefloxacin Mesylate Decoquinate Oxolinic Acid Ulifloxacin Dequalinium Chloride ALATROFLOXACIN Clinafloxacin Hydrochloride Finafloxacin Flumequine BESIFLOXACIN Dequalinium Dequalinium Acetate Ibafloxacin Olamufloxacin Delafloxacin

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