About: Nalidixic Acid

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Nalidixic Acid
rdfs:subClassOf	Urinary Anti-Infective Agent Quinolone Antibiotic
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Pharmacologic Substance
Preferred_Name	Nalidixic Acid
NSC_Code	82174
UMLS_CUI	C0027353
CAS_Registry	389-08-2
FDA_UNII_Code	3B91HWA56M
Contributing_Source	FDA
Chemical_Formula	C12H12N2O3
Legacy_Concept_Name	Nalidixic_Acid
CHEBI_ID	CHEBI:100147
FULL_SYN	1,8-Naphthyridine-3-carboxylic Acid, 1-ethyl-1,4-dihydro-7-methyl-4-oxo-SNNCI NALIDIXIC ACIDPTFDA3B91HWA56M Nalidixic AcidPTNCI 3-Carboxy-1-ethyl-7-methyl-1,8-naphthidin-4-oneSNNCI Nalidixic AcidPTDCP510 Acide NalidixicoSYNCI NegGramBRNCI NalidixinSYNCI
DEFINITION	A synthetic quinolone and antibacterial agent with urinary tract antiseptic activity. Nalidixic acid concentrates in the renal tubules and bladder and exerts its local antibacterial actions by interference of DNA gyrase activity, thereby inhibiting DNA synthesis during bacterial replication in a dose-dependent manner. Nalidixic acid is active against most gram-negative organisms that cause urinary tract infections.NCI
code	C47630
sameAs	NALIDIXIC ACID
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0014437
is sameAs of	NALIDIXIC ACID NALIDIXIC ACID

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