About: Lomefloxacin Hydrochloride

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About: Lomefloxacin Hydrochloride Goto Sponge NotDistinct Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Lomefloxacin Hydrochloride
rdfs:subClassOf	Quinolone Antibiotic
Has_Free_Acid_Or_Base_Form	LOMEFLOXACIN
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Pharmacologic Substance
Preferred_Name	Lomefloxacin Hydrochloride
UMLS_CUI	C0770927
CAS_Registry	98079-52-8
FDA_UNII_Code	9VC7S3ZXXB
Contributing_Source	FDA
Chemical_Formula	C17H19F2N3O3.HCl
Legacy_Concept_Name	Lomefloxacin_Hydrochloride
CHEBI_ID	CHEBI:6518
FULL_SYN	Lomefloxacin HydrochloridePTNCI NY 198CNNCI LOMEFLOXACIN HYDROCHLORIDEPTFDA9VC7S3ZXXB MaxaquinBRNCI MazaquinSYNCI (+-)-1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid, monohydrochlorideSNNCI
DEFINITION	The hydrochloride salt form of lomefloxacin, a synthetic broad-spectrum fluoroquinolone with antibacterial activity. Lomefloxacin hydrochloride inhibits DNA gyrase, a type II topoisomerase involved in the induction or relaxation of supercoiling during DNA replication. This inhibition leads to a decrease in DNA synthesis during bacterial replication, resulting in cell growth inhibition and eventually cell lysis.NCI
code	C47587
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0323321
is Has_Salt_Form of	LOMEFLOXACIN
is sameAs of	LOMEFLOXACIN HYDROCHLORIDE

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