About: Mitomycin Antineoplastic Antibiotic     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Mitomycin Antineoplastic Antibiotic
rdfs:subClassOf
Semantic_Type
  • Chemical Viewed Functionally
Preferred_Name
  • Mitomycin Antineoplastic Antibiotic
UMLS_CUI
  • C0026254
Accepted_Therapeutic_Use_For
  • Anal cancer; Bladder cancer; Breast cancer; Bronchogenic cancer; Cervical cancer; Colorectal cancer; Esophageal cancer; Gastric carcinoma; Head and neck cancer; Liver cancer; Pancreatic carcinoma; Pterygia
In_Clinical_Trial_For
  • Anal cancer; Bladder cancer; Breast cancer; Liver cancer; Liver metastases; Mesothelioma; Non-small cell lung cancer
ALT_DEFINITION
  • An anticancer drug that belongs to the family of drugs called antitumor antibiotics.NCI-GLOSS
Legacy_Concept_Name
  • Mitomycin_Antibiotic
CHEBI_ID
  • CHEBI:25357
FULL_SYN
  • Mitomycin Antineoplastic AntibioticPTNCI
  • mitomycinPTNCI-GLOSSCDR0000045538
DEFINITION
  • Any of a class of anti-tumor antibiotics acting as alkylating agents. All mitomycins have the backbone of methyl, aziridine, pyrrolo, indole, and dione moieties. Bioreductively activated mitomycin antibiotics generate oxygen radicals and alkylate DNA, forming inter-strand cross-links and inhibiting DNA synthesis.NCI
code
  • C663
sameAs
http://linked.open...y/mesh/hasConcept
is rdfs:subClassOf of
is sameAs of
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