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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Porfiromycin
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Antibiotic
  • Organic Chemical
Preferred_Name
  • Porfiromycin
NSC_Code
  • 56410
UMLS_CUI
  • C0032697
CAS_Registry
  • 801-52-5
FDA_UNII_Code
  • H1WK901OA6
Contributing_Source
  • FDA
ALT_DEFINITION
  • A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called anticancer antibiotics.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 39610
PDQ_Closed_Trial_Search_ID
  • 39610
Chemical_Formula
  • C16H20N4O5
Legacy_Concept_Name
  • Porfiromycin
FULL_SYN
  • PORFIROMYCINPTFDAH1WK901OA6
  • N-Methylmitomycin CSYDTPNSC0056410
  • PorfiromycinPTNCI
  • Azirino[2',3':3,4]pyrrolo[1, 2-a]indole-4,7-dione, 6-amino-1,1a,2,8,8a, 8b-hexahydro-8-(hydroxymethyl)-8a- methoxy-1,5-dimethyl-, carbamate (ester)(8CI)SNNCI
  • PorfiromycineSYNCI
  • PorphyromycinSYNCI
  • Azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione, 6-amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b- hexahydro-8a-methoxy-1,5-dimethyl-,[1aR-(1a.alpha.,8.beta., 8a.alpha.,8b.alpha.)]- (9CI)SYDTPNSC0056410
  • PorfiromycineSYDTPNSC0056410
  • PorphyromycinSYDTPNSC0056410
  • porfiromycinPTNCI-GLOSSCDR0000045235
  • MethylmitomycinSYNCI
  • Methyl MitomycinSYNCI
  • Azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione, 6-amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-1,5-dimethyl-,[1aR-(1a.alpha.,8.beta., 8a.alpha.,8b.alpha.)]- (9CI)SNNCI
  • Azirino[2',3':3,4]pyrrolo[1, 2-a]indole-4,7-dione, 6-amino-1,1a,2,8,8a, 8b-hexahydro-8-(hydroxymethyl)-8a- methoxy-1,5-dimethyl-, carbamate (ester) (8CI)SYDTPNSC0056410
  • ENT-50825SYDTPNSC0056410
  • [1aS-(1a alpha,8beta,8a alpha,8b alpha)]-6-amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-1,5-dimethylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dioneSNNCI
  • MITOMYCIN, METHYLSYDTPNSC0407676
  • U-14743CNNCI
  • Methyl Mitomycin CSYNCI
  • U-14,743CNNCI
  • N-methylmitomycin CSNNCI
  • PromycinBRNCI
  • ENT-50825CNNCI
  • Mitomycin, methyl-SYDTPNSC0407676
  • Methyl mitomycin CSYDTPNSC0056410
DEFINITION
  • An N-methyl derivative of the antineoplastic antibiotic mitomycin C isolated from the bacterium Streptomyces ardus and other Streptomyces bacterial species. Bioreduced porfiromycin generates oxygen radicals and alkylates DNA, producing interstrand cross-links and single-strand breaks, thereby inhibiting DNA synthesis. Porfiromycin is preferentially toxic to hypoxic cells. (NCI04)NCI
code
  • C763
sameAs
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