About: Mitomycin B     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Mitomycin B
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Antibiotic
  • Organic Chemical
Preferred_Name
  • Mitomycin B
NSC_Code
  • 75987
UMLS_CUI
  • C0128596
CAS_Registry
  • 4055-40-7
FDA_UNII_Code
  • VT1IGL3D7V
Contributing_Source
  • FDA
Chemical_Formula
  • C16H19N3O6
Legacy_Concept_Name
  • Mitomycin_B
FULL_SYN
  • Mitomycin BPTNCI
  • Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 1,1a,2,8,8a,8b-hexahydro-8a-hydroxy-8-(hydroxymethyl)-6-methoxy-1,5-dimethyl-, 8-carbamateSNNCI
  • MITOMYCIN BPTFDAVT1IGL3D7V
  • Mitomycin BSYDTPNSC0075987
DEFINITION
  • A methylazirinopyrroloindoledione antineoplastic antibiotic isolated from the bacterium Streptomyces caespitosus. Bioreduced mitomycin B generates oxygen radicals, alkylates DNA, and produces interstrand DNA cross-links, thereby inhibiting DNA synthesis. (NCI04)NCI
code
  • C1392
http://linked.open...y/mesh/hasConcept
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