About: Metallothionein analysis in prostate carcinoma at DNA, RNA and protein level.

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Metallothionein analysis in prostate carcinoma at DNA, RNA and protein level. Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Projekt, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/domain/vavai/Projekt
rdfs:seeAlso	http://www.isvav.cz/projectDetail.do?rowId=GP301/09/P436
Description	An important goal for the biomedical research community is the identification of disease-specific biomarkers. The hope is that these novel markers will be useful in the clinic by enabling early diagnosis of patients, improving prognosis, or serving as new therapeutic targets. In our study we intend to analyze in detail metallothionein as a new potential biomarker of tumor diseases specially in prostate carcinoma. This protein is a low-molecular intracellular molecule which can play an important role in heavy metal homeostasis in living organisms. Less is known about molecular mechanisms of MT expression. Overexpression of metallothioneins is studied as a new prognostic marker in a number of malignant and high grading tumors. Our efforts will be thus focused mainly on detection of MT genes (MT-1A, MT-2A), products of transcription and translation using standart electrophoretic, PCR and new biophysical methods. (en) Podrobné studium genové exprese metalothioneinů (MT-1A a MT2-A) v buňkách karcinomu prostaty na úrovni DNA, RNA a proteinu pomocí nových biofyzikálních metod. Srovnání a vzájemná korelace hodnot běžně používaného markeru (PSA) s hodnotami, které budou získány analýzou metalothioneinů.
Title	Metallothionein analysis in prostate carcinoma at DNA, RNA and protein level. (en) Analýza metalothioneinu u karcinomu prostaty na úrovni DNA, RNA a proteinu.
skos:notation	GP301/09/P436
http://linked.open...avai/cep/aktivita	Post-graduate (doctorate) grants
http://linked.open...kovaStatniPodpora	http://linked.opendata.cz/resource/domain/vavai/projekt/GP301%2F09%2FP436/celkovaStatniPodpora
http://linked.open...ep/celkoveNaklady	http://linked.opendata.cz/resource/domain/vavai/projekt/GP301%2F09%2FP436/celkoveNaklady
http://linked.open...datumDodatniDoRIV	2015-03-02 (xsd:date)
http://linked.open...i/cep/druhSouteze	VS - Veřejná soutěž ve výzkumu a vývoji
http://linked.open...ep/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open.../cep/fazeProjektu	91733829
http://linked.open...ai/cep/hlavniObor	FD - Onkologie a hematologie
http://linked.open...hodnoceniProjektu	U - Uspěl podle zadání, tj. byly splněny cíle a jeho předpokládané výsledky uvedené ve smlouvě / rozhodnutí o poskytnutí podpory
http://linked.open...vai/cep/kategorie	ZV - Základní výzkum
http://linked.open.../cep/klicovaSlova	metalothionein, karcinom prostaty, genová exprese, PCR, elektrochemická detekce (en)
http://linked.open...ep/partnetrHlavni	Lékařská fakulta
http://linked.open...inujicichPrijemcu	0 (xsd:int)
http://linked.open...cep/pocetPrijemcu	1 (xsd:int)
http://linked.open...ocetSpoluPrijemcu	0 (xsd:int)
http://linked.open.../pocetVysledkuRIV	42 (xsd:int)
http://linked.open...enychVysledkuVRIV	42 (xsd:int)
http://linked.open...lneniVMinulemRoce	2011-04-16 (xsd:date)
http://linked.open.../prideleniPodpory	http://linked.opendata.cz/resource/domain/vavai/cep/prideleniPodpory/301%2F09%2FP436
http://linked.open...iciPoslednihoRoku	2011
http://linked.open...atUdajeProjZameru	2012
http://linked.open.../vavai/cep/soutez	SGA02009GA1PD
http://linked.open...usZobrazovaneFaze	DUU
http://linked.open...ai/cep/typPojektu	P - Projekt výzkumu a vývoje financovaný ze státního rozpočtu
http://linked.open...ep/ukonceniReseni	2011-12-31 (xsd:date)
http://linked.open.../cep/vedlejsiObor	CE - Biochemie EB - Genetika a molekulární biologie
http://linked.open...ep/zahajeniReseni	2009-01-01 (xsd:date)
http://linked.open...jektu+dodavatelem	The project gone according to plan both in terms of expertise and in terms of disbursement of funds. (en) Řešení projektu proběhlo podle plánu jak z hlediska odborného tak i z hlediska čerpání finančních prostředků. (cs)
http://linked.open...tniCyklusProjektu	ZBKU
http://linked.open.../cep/klicoveSlovo	PCR genová exprese karcinom prostaty metalothionein
is http://linked.open...vavai/riv/projekt of	Apopticky a proliferacni expresni profil u nadorovych prostatickych bunek Antioxidační aktivity nádorových buněk a vliv cytostatik na antioxidační status Analysis of thiol compounds and antioxidant activity in patients suffering from malignant disease Antioxidacni aktivita u nadorovych bunek, vliv cytostatika na oxidacni status Electrophoretic analysis fingerprint metallothionein in patients with prostate adenocarcinoma Insight to Physiology and Pathology of Zinc(II) Ions and Their Actions in Breast and Prostate Carcinoma Isolation of metallothionein from cells derived from aggressive form of high-grade prostate carcinoma using paramagnetic antibody-modified microbeads off-line coupled with electrochemical and electrophoretic analysis Molecular mechanisms of zinc in prostate cancer Sarkosinu Determination in urine of patients with prostate cancer Determination thiolovych compounds and antioxidant activity in cancer patients Clinical importance of matrix metalloproteinases Determination prostate specific antigen and testosterone in tumour cell lines with encore zinc and sarcosine as well as in prostate cancer patients Determination of sarcosine as possible tumour marker of prostate tumours and routine biochemical tests in urine samples Software for processing of catalytic metallothionein signals Zinek – molekulární mechanizmy u karcinomu prostaty Analysis of sarcosine by capillary electrophoresis Femtogram electroanalytical detection of prostatic specific antigen by Brdicka reaction Monitoring of the prostate tumour cells redox state and real-time proliferation by novel biophysical techniques and fluorescent staining Serum metallothionein in newly diagnosed patients with childhood solid tumours Bioanalytical study of tumour markers for prostate carcinoma at RNA and protein level Electrophoretic fingerprint metallothionein analysis as a potential prostate cancer biomarker Heavy metals in prostate cancer cell lines Effects of redox conditions and zinc(II) ions on metallothionein aggregation revealed by chip capillary electrophoresis Matrix metalloproteinases Zinek a jeho vztah k nádorům prostaty Metallothionein - Zinc- Prostate cancer: Pathogenesis and diagnostic use Biochemical profile of effect of deoxynivalenol supplemented by mouldy cereals on rats Determination of metallothionein, glutathione and thermostable protein fraction concentrations in tumour tissue from head and neck area Determination of sarcosine as possible tumour marker of prostate tumours Determination of serum prostate specific antigen in patients with tumours of prostate and tumour cell lines Paramagnetic microparticles in metallothionein and alpha-methylacyl CoA racemase analysis in tumor cell lines derived from prostate carcinoma Fourier Transform and Cyclic Loop for Distinguishing of Catalytic Metallothionein Signals at Patients with Malignant Tumours Hladina metalothioneinu v krevnim seru u primarnich zachytu solidnich nadoru detskeho veku Zmeny hladiny metalothioneinu u bunecnych linii odvozenych z karcinomu prostaty Determination of metallothionein, glutathione and termostable protein fraction concentrations in tumour tissue from head and neck area Determination of sarcosine as possible tumour marker of prostate tumours Alpha-methylacyl-CoA racemase as a new marker in prostate cancer Determination of novel tumor markers in prostate carcinoma Effect of fluoranthene on pea plant (Pisum sativum L.) anatomical-morphological study Nové možnosti v laboratorní diagnostice karcinomu prostaty Study of zinc-dependent aggregation of metallothionein from human prostatic cancer cell lines Fourier Transform and Cyclic Loop for Distinguishing Catalytic Metallothionein Signals at Patient with Malignant Tumours
is http://linked.open...vavai/cep/projekt of	http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GP301%2F09%2FP436/2009/orjk%3A14110 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GP301%2F09%2FP436/2010/orjk%3A14110 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GP301%2F09%2FP436/2011/orjk%3A14110 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GP301%2F09%2FP436/2012/orjk%3A14110

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 48 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software