About: Biotechnology and Biomedicine Centre of the Academy of Sciences and Charles University

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Projekt, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/domain/vavai/Projekt
rdfs:seeAlso	http://www.biocev.eu http://www.isvav.cz/projectDetail.do?rowId=ED1.1.00/02.0109
Description	To establish a centre of excellence as part of the European Research Area and to guarantee development of modern biotechnologies and biomedicine in favour of scientific progress and society. The main objective of this project is to concentrate research teams of well renowned specialists with mutual professional interests, which are currently dispersed across various institutes of the Academy of Sciences of the Czech Republic and Charles University. Additionally, recruitment of young talented researchers and international experts is a necessary complement in order to establish the Biotechnology and Biomedicine Research Centre in Vestec (BIOCEV), with the ambition of creating a European centre of excellence. The presence of teams providing outputs of their unique basic research and of biotech experts, who will follow the research lines with their practical applications and innovations, in a single infrastructure with top-class instrumentation, will hence fill this considerable gap in the development of biotechnology industry in the Czech Republic. Participation in the networks of European consortia of Euro-BioImaging and INFRAFRONTIER as a part of ESFRI (European Strategy Forum on Research Infrastructures) as well as collaboration with renowned European partners is an essential asset of the BIOCEV centre. The research teams will recruit young researches with international post-doctoral experience as well as top Czech and international PhD students. At the same time, new teams will be created with the aim of recruiting researchers who have succeeded in competitive funding schemes such as EMBO (European Molecular Biology Organization) or Wellcome Trust and who have been granted to set up a new laboratory. Generation of the new knowledge basis together with the unique BIOCEV infrastructure will provide biotech companies with an exceptional way of cooperation in the form of contracted research and with professional staff training in the advanced biotechnology methods. (en) Vybudovat centrum excelentního výzkumu jako součást Evropského výzkumného prostoru a garantovat rozvoj moderních biotechnologií a biomedicíny ve prospěch vědeckého pokroku a společnosti. Hlavním cílem tohoto projektu je soustředit vzájemně se doplňující týmy renomovaných odborníků, dosud rozptýlených v několika partnerských pracovištích Akademie věd ČR a Univerzity Karlovy, doplnit je nově přijatými mladými talentovanými vědci a zahraničními experty a vytvořit biotechnologické a biomedicínské centrum výzkumu ve Vestci (BIOCEV) s ambicí evropského centra excelence. Soustředění týmů přinášejících unikátní poznatky základního výzkumu spolu s odborníky, kteří naváží na nové vědecké poznatky praktickými aplikacemi ve špičkově vybavené infrastruktuře, tak komplexně doplní citelnou mezeru v odborném zázemí pro rozvoj pokročilého biotechnologického průmyslu v ČR. Důležitým faktorem pro splnění této mise, je zapojení centra BIOCEV do sítí evropských konsorcií Euro-BioImaging a INFRAFRONTIER v rámci ESFRI (Evropské strategické fórum pro výzkumné infrastruktury) a spolupráce s renomovanými evropskými partnery. Vědecké týmy budou doplňovány mladými vědeckými pracovníky, kteří získali zkušenosti v zahraničních laboratořích a nejlepšími postgraduálními studenty (českými i zahraničními). Zároveň budou postupně vybudovány nové týmy s cílem získat pracovníky, kteří úspěšně prošli výběrem pro získání grantů EMBO (European Molecular Biology Organisation) či Welcome Trust a získali financování pro vybudování nové laboratoře. Nově vybudovaná znalostní základna, spojená v BIOCEV s unikátní infrastrukturou, poskytne biotechnologickým společnostem jedinečné možnosti spolupráce formou kontrahovaného výzkumu a školení zaměstnanců v pokročilých biotechnologických metodách.
Title	Biotechnology and Biomedicine Centre of the Academy of Sciences and Charles University (en) Biotechnologické a biomedicínské centrum Akademie věd a Univerzity Karlovy
skos:notation	ED1.1.00/02.0109
http://linked.open...avai/cep/aktivita	Operational Programme Research and Development for Innovation
http://linked.open...kovaStatniPodpora	http://linked.opendata.cz/resource/domain/vavai/projekt/ED1.1.00%2F02.0109/celkovaStatniPodpora
http://linked.open...ep/celkoveNaklady	http://linked.opendata.cz/resource/domain/vavai/projekt/ED1.1.00%2F02.0109/celkoveNaklady
http://linked.open...datumDodatniDoRIV	2015-04-02 (xsd:date)
http://linked.open...ep/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open.../cep/fazeProjektu	101072101
http://linked.open...ai/cep/hlavniObor	EB - Genetika a molekulární biologie
http://linked.open...vai/cep/kategorie	IF - Infrastruktura výzkumu a vývoje
http://linked.open.../cep/klicovaSlova	functional genomics; cellular biology; virology; structural biology; protein engineering; biomaterials; tissue engineering; diagnostic procedures; therapeutic procedures; Vestec; biology; ERA; microscopy; diagnostic; education; center of excelence; Infr… (en)
http://linked.open...ep/partnetrHlavni	Ústav molekulární genetiky AV ČR, v. v. i.
http://linked.open...inujicichPrijemcu	1 (xsd:int)
http://linked.open...cep/pocetPrijemcu	2 (xsd:int)
http://linked.open...ocetSpoluPrijemcu	5 (xsd:int)
http://linked.open.../pocetVysledkuRIV	130 (xsd:int)
http://linked.open...enychVysledkuVRIV	130 (xsd:int)
http://linked.open...lneniVMinulemRoce	2014-11-14 (xsd:date)
http://linked.open.../prideleniPodpory	http://linked.opendata.cz/resource/domain/vavai/cep/prideleniPodpory/0109%2F02%2F01
http://linked.open...iciPoslednihoRoku	2015
http://linked.open...atUdajeProjZameru	2015
http://linked.open...usZobrazovaneFaze	DRRVK
http://linked.open...ai/cep/typPojektu	P - Projekt výzkumu a vývoje financovaný ze státního rozpočtu
http://linked.open...ep/ukonceniReseni	2015-12-31 (xsd:date)
http://linked.open.../cep/vedlejsiObor	EI - Biotechnologie a bionika
http://linked.open...ep/zahajeniReseni	2012-02-01 (xsd:date)
http://linked.open...tniCyklusProjektu	ZBBK
http://linked.open.../cep/klicoveSlovo	functional genomics ERA Vestec biology biomaterials cellular biology center of excelence diagnostic diagnostic procedures education microscopy protein engineering structural biology therapeutic procedures tissue engineering virology
is http://linked.open...vavai/riv/projekt of	Downregulation of deoxycytidine kinase in cytarabine-resistant mantle cell lymphoma cells confers cross-resistance to nucleoside analogs gemcitabine, fludarabine and cladribine, but not to other classes of anti-lymphoma agents Different iron sources to study the physiology and biochemistry of iron metabolism in marine micro-algae Differential Expression and Processing of Matrix Metalloproteinase 19 Marks Progression of Gastrointestinal Diseases Distinct regions within the GluN2C subunit regulate the surface delivery of NMDA receptors The effect of dibenzo-p-dioxin- and dibenzofuran-contaminated soil on the earthworm Eisenia andrei Dip TIPS as a facile and versatile method for fabrication of polymer foams with controlled shape, size and pore architecture for bioengineering applications Kmenové buňky a imunita Partial deficiency of HIF-1 alpha stimulates pathological cardiac changes in streptozotocin-induced diabetic mice Pharmacogenomic analysis of retinoic-acid induced dyslipidemia in congenic rat model Photo-patterning of non-fouling polymers and biomolecules on paper Epigenetic Control of SPI1 Gene by CTCF and ISWI ATPase SMARCA5 ER to synapse trafficking of NMDA receptors Effect of H- and O-termination of nanocrystalline diamond films on cell adhesion and osteogenic differentiation Efficient gene targeting of the Rosa26 locus in mouse zygotes using TALE nucleases The effect of tetrabromobisphenol A on protamine content and DNA integrity in mouse spermatozoa Effect of zearalenone on reproductive parameters and expression of selected testicular genes in mice Gold Nanoparticles for High Resolution Imaging in Modern Immunocytochemistry Genomic Determinants of Triglyceride and Cholesterol Distribution into Lipoprotein Fractions in the Rat High density 3D localization microscopy using sparse support recovery Glioma-Associated Proteases Global changes in gene expression associated with phenotypic switching of wild yeast Giardia intestinalis Incorporates Heme into Cytosolic Cytochrome b(5) Hierarchical antifouling brushes for biosensing applications The Gene Expression of Human Endothelial Cells Is Modulated by Subendothelial Extracellular Matrix Proteins: Short-Term Response to Laminar Shear Stress Fusing catechol-driven surface anchoring with rapid hetero Diels-Alder ligation Manipulation of isolated brain nerve terminals by an external magnetic field using D-mannose-coated .gamma.-Fe2O3 nano-sized particles and assessment of their effects on glutamate transport Local dynamics of proteins and DNA evaluated from crystallographic B factors A retrotransposon-driven Dicer isoform directs endogenous small interfering RNA production in mouse oocytes Mechanistic basis of infertility of mouse intersubspecific hybrids Liver protective effect of ursodeoxycholic acid includes regulation of ADAM17 activity Interactions of serum with polyelectrolyte-stabilized liposomes: Cryo-TEM studies Involvement of Microtubular Network and Its Motors in Productive Endocytic Trafficking of Mouse Polyomavirus Involvement of the iron regulatory protein from Eisenia andrei earthworms in the regulation of cellular iron homeostasis Increasing the biological activity of IL-2 and IL-15 through complexing with anti-IL-2 mAbs and Il-15Ralfa-Fc chimera Injectable self-gelling composites for bone tissue engineering based on gellan gum hydrogel enriched with different bioglasses Increased expression of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels in reactive astrocytes following ischemia Sequence analysis of porothramycin biosynthetic gene cluster Towards dissecting molecular routes of intercellular communication in the tumour microenvironment: phenotypic plasticity of stem cell-associated markers in co-culture (carcinoma cell/fibroblast) systems Transcriptional and epigenetic regulation in the development of myeloid cells: normal and diseased myelopoiesis Tracking DNA and RNA Sequences at High Resolution Systemic AL amyloidosis with unusual cutaneous presentation unmasked by carotenoderma ThunderSTORM: a comprehensive ImageJ plug-in for PALM and STORM data analysis and super-resolution imaging Three-Dimensional Reconstruction of the S885A Mutant of Human Mitochondrial Lon Protease Toxoplasma gondii Decreases the Reproductive Fitness in Mice Systemic AL amyloidosis with unusual cutaneous presentation unmasked by carotenoderma Three-Dimensional Reconstruction of the S885A Mutant of Human Mitochondrial Lon Protease Three-dimensional super-resolution structured illumination microscopy with maximum a posteriori probability image estimation TATAA courses – 2 days Hands-on qPCR TATAA courses – 1 day Sample preparation and quality control of nucleic acids TATAA courses – 2 days Hands-on qPCR TATAA courses – 3 days Experimental design and statistical data analysis for qPCR

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