About: Platelet-Derived Growth Factor Receptor Beta     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Platelet-Derived Growth Factor Receptor Beta
equivalentClass
OMIM_Number
  • 173410
Semantic_Type
  • Amino Acid, Peptide, or Protein
Preferred_Name
  • Platelet-Derived Growth Factor Receptor Beta
UMLS_CUI
  • C0290068
Legacy_Concept_Name
  • Platelet-Derived_Growth_Factor_Receptor_Beta_Polypeptide
FULL_SYN
  • EC 2.7.10.1SYNCI
  • EC 2.7.1.112SYNCI
  • PDGF-R-BetaSYNCI
  • CD140 Antigen-Like Family Member BSYNCI
  • Beta Platelet-Derived Growth Factor ReceptorSYNCI
  • Platelet-Derived Growth Factor Receptor BetaPTNCI
  • CD140b AntigenSYNCI
  • Platelet-Derived Growth Factor Receptor Beta PolypeptideSYNCI
  • CD140bSYNCI
  • PDGFRBSYNCI
  • PDGFR-1SYNCI
  • Beta-Type Platelet-Derived Growth Factor ReceptorSYNCI
  • Platelet-Derived Growth Factor Receptor 1SYNCI
  • PDGFR-BetaSYNCI
Swiss_Prot
  • P09619
DEFINITION
  • Platelet-derived growth factor receptor beta (1106 aa, ~124 kDa) is encoded by the human PDGFRB gene. This protein plays a role in tyrosine phosphorylation and ligand-dependent signal transduction.NCI
DesignNote
  • The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETS, leukemia gene, results in chronic myelomonocytic leukemia. (from LocusLink)
code
  • C30164
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Target of
is sameAs of
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 116 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software