About: Cyclin-Dependent Kinase Inhibitor

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Attributes	Values
rdf:type	Class
rdfs:label	Cyclin-Dependent Kinase Inhibitor
rdfs:subClassOf	Protein Kinase Inhibitor
Semantic_Type	Chemical Viewed Functionally
Preferred_Name	Cyclin-Dependent Kinase Inhibitor
UMLS_CUI	C1511576
Legacy_Concept_Name	Cyclin-Dependent_Kinase_Inhibitor_Drug
FULL_SYN	Cyclin-Dependent Kinase InhibitorPTNCI CDK InhibitorSYNCI CDKIABNCI
DEFINITION	Any substance that inhibits cyclin-dependent kinase (CDK), an enzyme that catalyzes the addition of a phosphate group to a protein in the cell cycle regulation pathway. Inhibition of cyclin-dependent kinase results in cell cycle arrest and apoptosis.NCI
code	C2185
is rdfs:subClassOf of	CDK Inhibitor SNS-032 Seliciclib pan-CDK Inhibitor BAY1000394 Alvocidib Hydrochloride Indisulam PD-0332991 AG-024322 CDKI R547 CDKI AT7519 CDK Inhibitor P276-00 Alvocidib Dinaciclib CDK4 Inhibitor P1446A-05 CDK2/TRKA Inhibitor PHA-848125 AC CDK4/6 Inhibitor LEE011 CDK4/6 Dual Inhibitor LY2835219

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