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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • AG-024322
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • AG-024322
UMLS_CUI
  • C1706655
PDQ_Open_Trial_Search_ID
  • 459491
PDQ_Closed_Trial_Search_ID
  • 459491
Legacy_Concept_Name
  • AG-024322
FULL_SYN
  • AG-024322PTNCI
DEFINITION
  • A cyclin-dependent kinase (CDK) inhibitor with antineoplastic activity. AG-024322 selectively inhibits cyclin-dependent kinases (particularly CDK1,2 and 4), enzymes that regulate cell cycle progression. Inhibition of CDK may result in cell cycle arrest, induction of apoptosis, and inhibition of DNA replication and tumor cell proliferation.NCI
code
  • C52182
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