About: Increased expression of secretory actin-binding protein (SABP) on human spermatozoa is associated with poor semen quality

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About: Increased expression of secretory actin-binding protein (SABP) on human spermatozoa is associated with poor semen quality Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The specificity of newly generated Hs-16 monoclonal antibody (mAb) and the localization of the Hs-16-detected protein on human spermatozoa were determined. The Hs-16 mAb recognized secretory actin-binding protein (SABP) and partial co-localization of SABP and actin on spermatozoa was found. SABP was localized on various parts of spermatozoa, mainly in the sperm tail. Significantly increased expression of SABP was observed in men with pathological spermiograms. Thus, SABP can serve as a marker of defective sperm and may be associated with fertility failure. The specificity of newly generated Hs-16 monoclonal antibody (mAb) and the localization of the Hs-16-detected protein on human spermatozoa were determined. The Hs-16 mAb recognized secretory actin-binding protein (SABP) and partial co-localization of SABP and actin on spermatozoa was found. SABP was localized on various parts of spermatozoa, mainly in the sperm tail. Significantly increased expression of SABP was observed in men with pathological spermiograms. Thus, SABP can serve as a marker of defective sperm and may be associated with fertility failure. (en) Byla určena specificita nově připravené Hs-16 monoklonální protilátky a pomocí této protilátky lokalizován na spermiích protein, který rozpoznává. Hs-16 mAb detekuje sekreční aktin –vázající protein (SABP) a byla zjištěna částečná ko-lokalizace SABP a aktinu. SABP byl lokalizován na různých částech spermií, hlavně na bičíku. Významně zvýšená exprese SABP byla pozorována u mužů se špatnou kvalitou spermií. SABP může sloužit jako marker defektních spermií a může být spojen se selháním plodnosti. (cs)
Title	Increased expression of secretory actin-binding protein (SABP) on human spermatozoa is associated with poor semen quality Increased expression of secretory actin-binding protein (SABP) on human spermatozoa is associated with poor semen quality (en) Zvýšená exprese sekrečního aktin-vázajícího proteinu na lidských spermiích je spojena se špatnou kvalitou semene (cs)
skos:prefLabel	Increased expression of secretory actin-binding protein (SABP) on human spermatozoa is associated with poor semen quality Increased expression of secretory actin-binding protein (SABP) on human spermatozoa is associated with poor semen quality (en) Zvýšená exprese sekrečního aktin-vázajícího proteinu na lidských spermiích je spojena se špatnou kvalitou semene (cs)
skos:notation	RIV/68378050:_____/07:00097990!RIV08-AV0-68378050
http://linked.open.../vavai/riv/strany	1396;1404
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(AV0Z50200510), Z(AV0Z50520514), Z(AV0Z50520701)
http://linked.open...iv/cisloPeriodika	5
http://linked.open...vai/riv/dodaniDat	2008
http://linked.open...aciTvurceVysledku	Elzeinová, Fatima Čapková, Jana
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav molekulární genetiky AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	425938
http://linked.open...ai/riv/idVysledku	RIV/68378050:_____/07:00097990
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	monoclonal antibody; secretory actin-binding protein; human spermatozoa (en)
http://linked.open.../riv/klicoveSlovo	secretory actin-binding protein monoclonal antibody human spermatozoa
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[24D9EEED892D]
http://linked.open...i/riv/nazevZdroje	Human Reproduction
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...UplatneniVysledku	2007
http://linked.open...v/svazekPeriodika	22
http://linked.open...iv/tvurceVysledku	Elzeinová, Fatima Novák, Petr Čapková, Jana
http://linked.open...n/vavai/riv/zamer	Microorganisms in Research and Biotechnology Molekulárně genetické a buněčné základy klíčových biologických procesů: genová exprese, onkogeneze, replikace virů, imunita a vývoj organismů Establishing of the Biotechnology Institute ASCR
issn	0268-1161
number of pages	9 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Increased expression of secretory actin-binding protein (SABP) on human spermatozoa is associated with poor semen quality Increased expression of secretory actin-binding protein (SABP) on human spermatozoa is associated with poor semen quality Increased expression of secretory actin-binding protein (SABP) on human spermatozoa is associated with poor semen quality

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