About: Different effect of two synthetic coumarin-stilbene hybrid compounds on phagocyte activity

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Synthetic phenylcoumarin derivatives HHC (7-hydroxy-3-(4'-hydroxyphenyl) coumarin) and HHDC (7-hydroxy-3-(4'-hydroxyphenyl)-3,4-dihydrocoumarin) can affect ROS generation in human neutrophils and NO production by RAW 264.7 macrophages. The obtained results highlighted the different effects of HHC and HHDC on fagocyte functions, which might be due to their diverse free radical scavenging properties and lipophilicity features. Synthetic phenylcoumarin derivatives HHC (7-hydroxy-3-(4'-hydroxyphenyl) coumarin) and HHDC (7-hydroxy-3-(4'-hydroxyphenyl)-3,4-dihydrocoumarin) can affect ROS generation in human neutrophils and NO production by RAW 264.7 macrophages. The obtained results highlighted the different effects of HHC and HHDC on fagocyte functions, which might be due to their diverse free radical scavenging properties and lipophilicity features. (en)
Title	Different effect of two synthetic coumarin-stilbene hybrid compounds on phagocyte activity Different effect of two synthetic coumarin-stilbene hybrid compounds on phagocyte activity (en)
skos:prefLabel	Different effect of two synthetic coumarin-stilbene hybrid compounds on phagocyte activity Different effect of two synthetic coumarin-stilbene hybrid compounds on phagocyte activity (en)
skos:notation	RIV/68081707:_____/10:00391596!RIV13-MSM-68081707
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA203/07/1227), P(MEB0810013), Z(AV0Z40550506), Z(AV0Z50040507), Z(AV0Z50040702)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Lojek, Antonín Ambrožová, Gabriela
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Biofyzikální ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	254405
http://linked.open...ai/riv/idVysledku	RIV/68081707:_____/10:00391596
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	reactive species; phagocytosis; coumarin (en)
http://linked.open.../riv/klicoveSlovo	phagocytosis coumarin reactive species
http://linked.open...odStatuVydavatele	SE - Švédské království
http://linked.open...ontrolniKodProRIV	[E47D852C2E21]
http://linked.open...i/riv/nazevZdroje	Neuroendocrinology Letters
http://linked.open...in/vavai/riv/obor	BO
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	9 (xsd:int)
http://linked.open...vavai/riv/projekt	Molecular biological perspectives of the pharmacological modulation of the activation of professional phagocytes Photochemical preparation of oligomeric analogues of natural resveratrol derivatives and related stilbenoids
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	31
http://linked.open...iv/tvurceVysledku	Lojek, Antonín Ambrožová, Gabriela Harmatha, Juraj Drábiková, K. Jančinová, V. Perečko, T. Nosál, R. Šmidrkal, J. Račková, L.
http://linked.open...ain/vavai/riv/wos	000288061000014
http://linked.open...n/vavai/riv/zamer	Regulace biologických procesů: Chemické modulátory vybraných systémů významných pro medicínu a zemědělství Biophysics of dynamic structures and functions of biological systems Genome and epigenome: 1D and 3D Structure, Dynamics, Interactions with Proteins and Functions
issn	0172-780X
number of pages	6 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Different effect of two synthetic coumarin-stilbene hybrid compounds on phagocyte activity

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