About: Different features of the DNA binding mode of antitumor cis-amminedichlorido(cyclohexylamine)platinum(II) (JM118) and cisplatin in vitro

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About: Different features of the DNA binding mode of antitumor cis-amminedichlorido(cyclohexylamine)platinum(II) (JM118) and cisplatin in vitro Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	JM118 is the major metabolite of satraplatin. The results of DNA-protein cross-linking assay and DNA repair synthesis by cell-free extract showed a higher DNA-protein cross-linking efficiency of JM118 and less efficient removal from DNA of the adducts of JM118 in comparison with cisplatin. JM118 is the major metabolite of satraplatin. The results of DNA-protein cross-linking assay and DNA repair synthesis by cell-free extract showed a higher DNA-protein cross-linking efficiency of JM118 and less efficient removal from DNA of the adducts of JM118 in comparison with cisplatin. (en)
Title	Different features of the DNA binding mode of antitumor cis-amminedichlorido(cyclohexylamine)platinum(II) (JM118) and cisplatin in vitro Different features of the DNA binding mode of antitumor cis-amminedichlorido(cyclohexylamine)platinum(II) (JM118) and cisplatin in vitro (en)
skos:prefLabel	Different features of the DNA binding mode of antitumor cis-amminedichlorido(cyclohexylamine)platinum(II) (JM118) and cisplatin in vitro Different features of the DNA binding mode of antitumor cis-amminedichlorido(cyclohexylamine)platinum(II) (JM118) and cisplatin in vitro (en)
skos:notation	RIV/68081707:_____/10:00353781!RIV11-MSM-68081707
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GAP301/10/0598), P(IAA400040803), P(ME08017), P(ME10066), P(OC08003), P(OC09018), Z(AV0Z50040507), Z(AV0Z50040702), Z(MSM6198959216)
http://linked.open...iv/cisloPeriodika	11
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Kostrhunová, Hana Brabec, Viktor Kašpárková, Jana Vrána, Oldřich
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Biofyzikální ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	254365
http://linked.open...ai/riv/idVysledku	RIV/68081707:_____/10:00353781
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	JM118; DNA bending; DNA-protein cross-linking (en)
http://linked.open.../riv/klicoveSlovo	DNA bending DNA-protein cross-linking JM118
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[B436AD4A843F]
http://linked.open...i/riv/nazevZdroje	Chemical Research in Toxicology
http://linked.open...in/vavai/riv/obor	BO
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Platinum Metal Complexes as DNA-Protein Cross-Linking Agents Structure, recognition, and processing of DNA damage by metal-based compounds of biological significance Mechanism of antitumor activity of metallodrugs. DNA replication and repair of DNA damage Metallodrugs based on osmium, platinum and ruthenium complexes. From mechanistic studies to novel, more efficient chemotherapy of cancer Mechanistic studies related to targeted cancer chemotherapy with light-activated platinum and ruthenium antitumor agents Transition metal-based anticancer compounds. From mechanistic studies to innovatory cancer chemotherapy
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	23
http://linked.open...iv/tvurceVysledku	Brabec, Viktor Kostrhunová, Hana Kašpárková, Jana Suchánková, T. Vrána, Oldřich Gibson, D.
http://linked.open...ain/vavai/riv/wos	000284290500023
http://linked.open...n/vavai/riv/zamer	Biophysics of dynamic structures and functions of biological systems Genome and epigenome: 1D and 3D Structure, Dynamics, Interactions with Proteins and Functions Modulation of signalling and regulatory pathways in normal and cancer cells
issn	0893-228X
number of pages	10 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Different features of the DNA binding mode of antitumor cis-amminedichlorido(cyclohexylamine)platinum(II) (JM118) and cisplatin in vitro Different features of the DNA binding mode of antitumor cis-amminedichlorido(cyclohexylamine)platinum(II) (JM118) and cisplatin in vitro Different features of the DNA binding mode of antitumor cis-amminedichlorido(cyclohexylamine)platinum(II) (JM118) and cisplatin in vitro

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