About: Human fetal colon cells and colon cancer cells respond differently to butyrate and PUFAs

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About: Human fetal colon cells and colon cancer cells respond differently to butyrate and PUFAs Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Comparing human colon epithelial cell lines of fetal (FHC) and adenocarcinoma (HT-29, HCT-116) origin, we detected significant differences in proliferation, differentiation, and apoptotic response to the treatment of sodium butyrate (NaBt), arachidonic or docosahexaenoic acids, and their combination. Our results support the concept of modulation of NaBt effects by polyunsaturated fatty acids, especially of omega-3 type, in colonic cells in vitro with diverse impact in cell lines derived from normal or neoplastic epithelium. Comparing human colon epithelial cell lines of fetal (FHC) and adenocarcinoma (HT-29, HCT-116) origin, we detected significant differences in proliferation, differentiation, and apoptotic response to the treatment of sodium butyrate (NaBt), arachidonic or docosahexaenoic acids, and their combination. Our results support the concept of modulation of NaBt effects by polyunsaturated fatty acids, especially of omega-3 type, in colonic cells in vitro with diverse impact in cell lines derived from normal or neoplastic epithelium. (en)
Title	Human fetal colon cells and colon cancer cells respond differently to butyrate and PUFAs Human fetal colon cells and colon cancer cells respond differently to butyrate and PUFAs (en)
skos:prefLabel	Human fetal colon cells and colon cancer cells respond differently to butyrate and PUFAs Human fetal colon cells and colon cancer cells respond differently to butyrate and PUFAs (en)
skos:notation	RIV/68081707:_____/09:00332328!RIV10-AV0-68081707
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1QS500040507), P(GA301/07/1557), P(GA524/07/1178), Z(AV0Z50040507), Z(AV0Z50040702)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Kozubík, Alois Hofmanová, Jiřina Vaculová, Alena Hýžďalová, Martina Koubková, Zuzana
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Biofyzikální ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	318025
http://linked.open...ai/riv/idVysledku	RIV/68081707:_____/09:00332328
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	apoptosis; butyrate; cell differentiation (en)
http://linked.open.../riv/klicoveSlovo	cell differentiation butyrate apoptosis
http://linked.open...odStatuVydavatele	DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV	[87600866BC41]
http://linked.open...i/riv/nazevZdroje	Molecular Nutrition & Food Research
http://linked.open...in/vavai/riv/obor	BO
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Lipid nutrition compounds - modulation of their effects and possibilities of practical application Novel anticancer platinum complexes - mechanisms of their action and innovative chemotherapy strategies Importance of cell lipid changes during differentiation and apoptosis of colon epithelial cells
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	53
http://linked.open...iv/tvurceVysledku	Hofmanová, Jiřina Kozubík, Alois Vaculová, Alena Hýžďalová, Martina Koubková, Zuzana
http://linked.open...ain/vavai/riv/wos	000271475300013
http://linked.open...n/vavai/riv/zamer	Biophysics of dynamic structures and functions of biological systems Genome and epigenome: 1D and 3D Structure, Dynamics, Interactions with Proteins and Functions
issn	1613-4125
number of pages	12 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Human fetal colon cells and colon cancer cells respond differently to butyrate and PUFAs Human fetal colon cells and colon cancer cells respond differently to butyrate and PUFAs Human fetal colon cells and colon cancer cells respond differently to butyrate and PUFAs Human fetal colon cells and colon cancer cells respond differently to butyrate and PUFAs

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