About: DNA interactions of dinuclear RuII arene antitumor complexes in cell-free media

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About: DNA interactions of dinuclear RuII arene antitumor complexes in cell-free media Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	DNA modifications by new dinuclear RuII arene compounds were studied. The complexes bind DNA forming intrastrand and interstrand cross-links in one DNA molecule. An intriguing aspect of the DNA-binding mode of these dinuclear RuII compounds is that they can crosslink two DNA duplexes and also proteins to DNA. DNA modifications by new dinuclear RuII arene compounds were studied. The complexes bind DNA forming intrastrand and interstrand cross-links in one DNA molecule. An intriguing aspect of the DNA-binding mode of these dinuclear RuII compounds is that they can crosslink two DNA duplexes and also proteins to DNA. (en) Byly studovány modifikace DNA sérií nových dinukleárních Ru komplexů. Tyto komplexy tvoří na molekule DNA vnitrořetězcové i meziřetězcové můstky. Kromě toho jsou schopny vytvářet také můstky mezi dvěma molekulami DNA nebo DNA a proteiny. (cs)
Title	DNA interactions of dinuclear RuII arene antitumor complexes in cell-free media Interakce DNA s protinádorově aktivními dinukleárními RuII komplexy in vitro (cs) DNA interactions of dinuclear RuII arene antitumor complexes in cell-free media (en)
skos:prefLabel	DNA interactions of dinuclear RuII arene antitumor complexes in cell-free media Interakce DNA s protinádorově aktivními dinukleárními RuII komplexy in vitro (cs) DNA interactions of dinuclear RuII arene antitumor complexes in cell-free media (en)
skos:notation	RIV/68081707:_____/09:00320869!RIV09-AV0-68081707
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1QS500040581), P(KAN200200651), P(LC06030), P(ME08017), P(OC08003), Z(AV0Z50040507), Z(AV0Z50040702)
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2009
http://linked.open...aciTvurceVysledku	Brabec, Viktor Nováková, Olga
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Biofyzikální ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	311001
http://linked.open...ai/riv/idVysledku	RIV/68081707:_____/09:00320869
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	dinuclear ruthenium complex; DNA; cross-links (en)
http://linked.open.../riv/klicoveSlovo	DNA cross-links dinuclear ruthenium complex
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[D3606C8B9487]
http://linked.open...i/riv/nazevZdroje	Biochemical Pharmacology
http://linked.open...in/vavai/riv/obor	BO
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Metallodrugs, design and mechansim of action Platinum Metal Complexes as DNA-Protein Cross-Linking Agents Structure, recognition, and processing of DNA damage by metal-based compounds of biological significance Nanoparticulate and supramolecular systems for targeted drug delivery Biomolecular centre
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	77
http://linked.open...iv/tvurceVysledku	Brabec, Viktor Nováková, Olga Hartinger, Ch. G. Keppler, B. K. Nazarov, A. A.
http://linked.open...ain/vavai/riv/wos	000262935900007
http://linked.open...n/vavai/riv/zamer	Biophysics of dynamic structures and functions of biological systems Genome and epigenome: 1D and 3D Structure, Dynamics, Interactions with Proteins and Functions
issn	0006-2952
number of pages	11 (xsd:int)
is http://linked.open...avai/riv/vysledek of	DNA interactions of dinuclear RuII arene antitumor complexes in cell-free media DNA interactions of dinuclear RuII arene antitumor complexes in cell-free media

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