About: Cationic nonsymmetric transplatinum complexes with piperidinopiperidine ligands. Preparation, characterization, in vitro cytotoxicity, in vivo toxicity, and anticancer efficacy studies     Goto   Sponge   NotDistinct   Permalink

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Description
  • Byla připravena a charakterizována série komplexů obecného vzorce trans-[PtCl2(Am)(pip-pip)].HCl, kde pip-pip je 4-piperidinopiperidin a Am is NH3, methylamin, dimethylamin, n-propylamin, isopropylamin, n-butylamin nebo cyclohexylamin a byly vyhodnoceny jejich cytotoxické vlastnosti v ovariálních a střevních nádorových buňkách. (cs)
  • A series of complexes of the general formula trans-[PtCl2(Am)(pip-pip)].HCl where pip-pip is 4-piperidinopiperidine and Am is NH3, methylamine, dimethylamine, n-propylamine, isopropylamine, n-butylamine, or cyclohexylamine were prepared and characterized, and their cytotoxic properties against ovarian and colon cancer cells were evaluated.
  • A series of complexes of the general formula trans-[PtCl2(Am)(pip-pip)].HCl where pip-pip is 4-piperidinopiperidine and Am is NH3, methylamine, dimethylamine, n-propylamine, isopropylamine, n-butylamine, or cyclohexylamine were prepared and characterized, and their cytotoxic properties against ovarian and colon cancer cells were evaluated. (en)
Title
  • Cationic nonsymmetric transplatinum complexes with piperidinopiperidine ligands. Preparation, characterization, in vitro cytotoxicity, in vivo toxicity, and anticancer efficacy studies
  • Kationtové nesymetrické komplexy transplatiny s piperidinopiperidinovými ligandy. Příprava, charakterizace, cytotoxicita in vitro, toxicita in vivo a protinádorová účinnost (cs)
  • Cationic nonsymmetric transplatinum complexes with piperidinopiperidine ligands. Preparation, characterization, in vitro cytotoxicity, in vivo toxicity, and anticancer efficacy studies (en)
skos:prefLabel
  • Cationic nonsymmetric transplatinum complexes with piperidinopiperidine ligands. Preparation, characterization, in vitro cytotoxicity, in vivo toxicity, and anticancer efficacy studies
  • Kationtové nesymetrické komplexy transplatiny s piperidinopiperidinovými ligandy. Příprava, charakterizace, cytotoxicita in vitro, toxicita in vivo a protinádorová účinnost (cs)
  • Cationic nonsymmetric transplatinum complexes with piperidinopiperidine ligands. Preparation, characterization, in vitro cytotoxicity, in vivo toxicity, and anticancer efficacy studies (en)
skos:notation
  • RIV/68081707:_____/06:00040265!RIV07-AV0-68081707
http://linked.open.../vavai/riv/strany
  • 4665;4673
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(1QS500040581), P(GA305/05/2030), P(NR8562), Z(AV0Z50040507)
http://linked.open...iv/cisloPeriodika
  • 15
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 467882
http://linked.open...ai/riv/idVysledku
  • RIV/68081707:_____/06:00040265
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • transplatinum complexes; piperidinopiperidine ligands; ligands (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [3973AF2EE88E]
http://linked.open...i/riv/nazevZdroje
  • Journal of Medicinal Chemistry
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 49
http://linked.open...iv/tvurceVysledku
  • Brabec, Viktor
  • Kašpárková, Jana
  • Perez, J. M.
  • Gibson, D.
  • Najajreh, Y.
  • Ardeli-Tzaraf, Y.
  • Barenholz, Y.
  • Jawbry, S.
  • Khazanov, E.
http://linked.open...n/vavai/riv/zamer
issn
  • 0022-2623
number of pages
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