About: Antileukotrienic phenethylamido derivatives of arylalkanoic acids in the treatment of ulcerative colitis

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Antileukotrienic phenethylamido derivatives of arylalkanoic acids in the treatment of ulcerative colitis Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	We synthetised new arylalkanoic acid derivatives bearing methyl(phenethyl)amino groups. These compounds have ability to inhibit the biosynthesis of pro-inflammatory mediator LTB4. Furthermore, we found that 4 of these compounds are more active in the animal model of ulcerative colitis than sulfasalazine, and could therefore be considered as good candidates for ulcerative colitis therapy We synthetised new arylalkanoic acid derivatives bearing methyl(phenethyl)amino groups. These compounds have ability to inhibit the biosynthesis of pro-inflammatory mediator LTB4. Furthermore, we found that 4 of these compounds are more active in the animal model of ulcerative colitis than sulfasalazine, and could therefore be considered as good candidates for ulcerative colitis therapy (en)
Title	Antileukotrienic phenethylamido derivatives of arylalkanoic acids in the treatment of ulcerative colitis Antileukotrienic phenethylamido derivatives of arylalkanoic acids in the treatment of ulcerative colitis (en)
skos:prefLabel	Antileukotrienic phenethylamido derivatives of arylalkanoic acids in the treatment of ulcerative colitis Antileukotrienic phenethylamido derivatives of arylalkanoic acids in the treatment of ulcerative colitis (en)
skos:notation	RIV/61388971:_____/09:00335377!RIV10-AV0-61388971
http://linked.open...avai/riv/aktivita	P S Z
http://linked.open...avai/riv/aktivity	P(GD310/03/H147), P(LN00B125), S, Z(AV0Z50200510), Z(MSM0021620822)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Kverka, Miloslav
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Mikrobiologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	303481
http://linked.open...ai/riv/idVysledku	RIV/61388971:_____/09:00335377
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	N-Phenethyl-2-arylacetamides; Antileukotrienic activity; QSAR (en)
http://linked.open.../riv/klicoveSlovo	Antileukotrienic activity N-Phenethyl-2-arylacetamides QSAR
http://linked.open...odStatuVydavatele	FR - Francouzská republika
http://linked.open...ontrolniKodProRIV	[E6C7D0A30EC8]
http://linked.open...i/riv/nazevZdroje	European Journal of Medicinal Chemistry
http://linked.open...in/vavai/riv/obor	EC
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	Regulatory mechanisms of the immune responses and their potential for development of new preventive and therapeutic strategies Research Centre of Structure and Mechanism of Action of Potential Drugs
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	44
http://linked.open...iv/tvurceVysledku	Kuchař, M. Kverka, Miloslav Macháček, M. Jandera, A. Junek, R. Panajotová, V. Šatinský, D.
http://linked.open...ain/vavai/riv/wos	000262693700036
http://linked.open...n/vavai/riv/zamer	Microorganisms in Research and Biotechnology Research of new drug structures
issn	0223-5234
number of pages	13 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Antileukotrienic phenethylamido derivatives of arylalkanoic acids in the treatment of ulcerative colitis Antileukotrienic phenethylamido derivatives of arylalkanoic acids in the treatment of ulcerative colitis Antileukotrienic phenethylamido derivatives of arylalkanoic acids in the treatment of ulcerative colitis Antileukotrienic phenethylamido derivatives of arylalkanoic acids in the treatment of ulcerative colitis

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 58 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software