About: Chemical cross-linking and mass spectrometry as structure determination tools

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Chemical cross-linking is becoming a valuable tool for the high-order structure determination of proteins and protein complexes. Cross-linking methodology is able to provide low-resolution structures when at least something is known already about the proteins under investigation. The suitability of top-down and bottom-up methodologies is discussed and further potential applications of chemical cross-linking of proteins, as well as combinations with other techniques such as hydrogen/ deuterium exchange and molecular modeling, are suggested Chemical cross-linking is becoming a valuable tool for the high-order structure determination of proteins and protein complexes. Cross-linking methodology is able to provide low-resolution structures when at least something is known already about the proteins under investigation. The suitability of top-down and bottom-up methodologies is discussed and further potential applications of chemical cross-linking of proteins, as well as combinations with other techniques such as hydrogen/ deuterium exchange and molecular modeling, are suggested (en) Chemické zesítění proteinu a následná analýza míst zesítění pomocí hmotnostní spektrometrie mohou vést k získání trojrozměrné struktury proteinu o nízkém rozlišení. Možnost použití různých přístupů k identifikaci míst zesítění, a kombinace dané techniky s technikou H/D výměny a použití přístupů modelování molekul je zde diskutováno (cs)
Title	Chemical cross-linking and mass spectrometry as structure determination tools Chemical cross-linking and mass spectrometry as structure determination tools (en) Chemické zesítění a hmotnostní spektrometrie jako nástroj sloužící k určování struktury proteinů (cs)
skos:prefLabel	Chemical cross-linking and mass spectrometry as structure determination tools Chemical cross-linking and mass spectrometry as structure determination tools (en) Chemické zesítění a hmotnostní spektrometrie jako nástroj sloužící k určování struktury proteinů (cs)
skos:notation	RIV/61388971:_____/07:00095370!RIV08-AV0-61388971
http://linked.open.../vavai/riv/strany	105;113
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(KJB400200501), P(LC545), Z(AV0Z50200510)
http://linked.open...iv/cisloPeriodika	-
http://linked.open...vai/riv/dodaniDat	2008
http://linked.open...aciTvurceVysledku	Novák, Petr
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Mikrobiologický ústav AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	413449
http://linked.open...ai/riv/idVysledku	RIV/61388971:_____/07:00095370
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	cross-linking; protein; high order structure (en)
http://linked.open.../riv/klicoveSlovo	cross-linking protein high order structure
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[89193B08906A]
http://linked.open...i/riv/nazevZdroje	European Journal of Mass Spectrometry
http://linked.open...in/vavai/riv/obor	EE
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	2 (xsd:int)
http://linked.open...vavai/riv/projekt	Functional Organisation of the Cell Determination of the Three-Dimensional Structure of Secreted Aspartic Proteases Using Chemical Cross-Linking and High Resolution Mass Spectrometry
http://linked.open...UplatneniVysledku	2007
http://linked.open...v/svazekPeriodika	13
http://linked.open...iv/tvurceVysledku	Novák, Petr Giannakopulos, A.
http://linked.open...n/vavai/riv/zamer	Microorganisms in Research and Biotechnology
issn	1469-0667
number of pages	9 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Chemical cross-linking and mass spectrometry as structure determination tools Chemical cross-linking and mass spectrometry as structure determination tools Chemical cross-linking and mass spectrometry as structure determination tools

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