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rdf:type
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Description
| - Combining explicit-solvent molecular dynamics simulation and single molecule fluorescence spectroscopy approaches, we find that a ribozyme from a subviral plant pathogen exhibits a coupled hydrogen bonding network that communicates dynamic structural rearrangements throughout the catalytic core in response to site-specific chemical modification. Trapped long-residency water molecules are critical for this network.
- Combining explicit-solvent molecular dynamics simulation and single molecule fluorescence spectroscopy approaches, we find that a ribozyme from a subviral plant pathogen exhibits a coupled hydrogen bonding network that communicates dynamic structural rearrangements throughout the catalytic core in response to site-specific chemical modification. Trapped long-residency water molecules are critical for this network. (en)
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Title
| - Trapped water molecules are essential to structural dynamics and function of a ribozyme
- Trapped water molecules are essential to structural dynamics and function of a ribozyme (en)
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skos:prefLabel
| - Trapped water molecules are essential to structural dynamics and function of a ribozyme
- Trapped water molecules are essential to structural dynamics and function of a ribozyme (en)
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skos:notation
| - RIV/00216224:14310/06:00017097!RIV10-MSM-14310___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(1QS500040581), P(GA203/05/0009), P(GA203/05/0388), P(LC06030), P(LC512), Z(AV0Z40550506), Z(AV0Z50040507), Z(MSM0021622413)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216224:14310/06:00017097
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - coupled molecular motions; hairpin ribozyme; molecular dynamics; proton wire (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - The Proceedings of the National Academy of Sciences
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Réblová, Kamila
- Šponer, Jiří
- Nils, Walter
- Rhodes, Maria
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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is http://linked.open...avai/riv/vysledek
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