About: Brain and nervous systems

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Projekt, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/domain/vavai/Projekt
rdfs:seeAlso	http://www.isvav.cz/projectDetail.do?rowId=KSK2011602
Description	The project provides considerable progress of our knowledge of the nervous system functions in man and animals as well as the application of new results in clinical medicine. This project will be based on the research potential of 14 advanced internationally recognized laboratories, joint effort of which will enable to research on molecular, cellular and system level. It will be directed to 1) complex study of the input, transmission and processing of information in the brain and in the peripheral nervous system under normal and pathological conditions, 2) analysis of physiological basis of motivated behavior, endogenous rhythms and memory, and 3) origin of neuromotor seizures and neurodegenerative diseases with the aim to find possibleprevention and/or therapy of pathological alterations of nervous functions. (en) Projekt zajistí podstatné prohloubení znalostí o funkcích nervové soustavy člověka a zvířat a využití nových poznatků v klinické medicíně. Využije kapacit čtrnácti vyspělých laboratoří, jejichž práce dosáhla světového uznání a jejichž společné úsilí umožní práce na molekulové, buněčné a systémové úrovni. Zaměří se na komplexní studium vstupu, přenosu a zpracování informací v mozku i periferní nervové soustavě za normálních a patologických podmínek, na analýzu fyziologických základů motivovaného chování, endogenních rytmů a paměti a na vznik neuromotorických záchvatů a neurodegenerativních onemocnění s hledáním možnosti prevence a terapie patologicky narušených funkcí.
Title	Brain and nervous systems (en) Mozek a nervové systémy
skos:notation	KSK2011602
http://linked.open...avai/cep/aktivita	Scheme of the development of investigative research in key branches of science
http://linked.open...kovaStatniPodpora	http://linked.opendata.cz/resource/domain/vavai/projekt/KSK2011602/celkovaStatniPodpora
http://linked.open...ep/celkoveNaklady	http://linked.opendata.cz/resource/domain/vavai/projekt/KSK2011602/celkoveNaklady
http://linked.open...ep/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open.../cep/fazeProjektu	596426
http://linked.open...ai/cep/hlavniObor	ED - Fyziologie
http://linked.open...hodnoceniProjektu	V - Vynikající výsledky (s mezinárodním významem apod.). Zároveň byly splněny cíle a předpokládané výsledky uvedené ve smlouvě / rozhodnutí o poskytnutí podpory.
http://linked.open...ep/partnetrHlavni	Fyziologický ústav AV ČR, v.v.i.
http://linked.open...inujicichPrijemcu	0 (xsd:int)
http://linked.open...cep/pocetPrijemcu	1 (xsd:int)
http://linked.open...ocetSpoluPrijemcu	0 (xsd:int)
http://linked.open.../pocetVysledkuRIV	49 (xsd:int)
http://linked.open...enychVysledkuVRIV	49 (xsd:int)
http://linked.open...iciPoslednihoRoku	2001
http://linked.open...atUdajeProjZameru	2001
http://linked.open...usZobrazovaneFaze	DUU
http://linked.open...ai/cep/typPojektu	P - Projekt výzkumu a vývoje financovaný ze státního rozpočtu
http://linked.open.../cep/vedlejsiObor	CE - Biochemie FH - Neurologie, neurochirurgie, neurovědy
http://linked.open...jektu+dodavatelem	Byly získány kvalitní výsledky při studiu základních mechanizmů činnosti nervové soustavy s výhledem jejich využití v lékařské praxi. (cs)
http://linked.open...tniCyklusProjektu	ZBBBKU
is http://linked.open...vavai/riv/projekt of	Diffusion Barriers Evoked in the Rat Cortex by Reactive Astrogliosis. Volume transmission in the CNS and its relevance for neuropsychopharmacology. Continuous place avoidance task reveals differences in spatial navigation in male and female rats. Behavioral and metabolic changes in immature rats during seizures induced by homocysteic acid: the protective effect of NMDA and Non-NMDA receptor antagonists. Conjoint control of hippocampal place cell firing by two visual stimuli. Conjoint control of hippocampal place cell firing by two visual stimuli: I. The effects of moving the stimuli on firing field positions. Axotomy-induced changes in the properties of (S)-alfa-Amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor channels in rat motoneurons. Cyclic AMP synchronizes evoked quantal release at frog neuromuscular junctions. Gate for photic resetting of intrinsic rhythmicity of the rat suprachiasmatic nucleus under a long photoperiod. Hormones, subjective night and season of the year. Functional inactivation of dorsal hippocampus impairs active place avoidance in rats. In vitro entrainment of the circadian rhythm of vasopressin-releasing cells in suprachiasmatic nucleus by vasoactive intestinal polypeptide. Glial influence on neuronal signaling. Extracellular Diffusion Parameters in Spinal Cord and Filum Terminale of the Frog. Multidimensional counting processes and evoked neuronal activity. Melatonin inhibits pituitary adenylyl cyclase-activating polypeptide-induced increase of cyclic AMP accumulation and /Ca 2+/i in cultured cells of neonatal rat pituitary. Molecular and functional properties of synaptically activated NMDA receptors in neonatal motoneurons in rat spinal cord slices. Neurotoxicity of NAAG in vivo is sensitive to NMDA antagonists and mGluR II ligands. MDP and 5-HT receptors. Does MDP interact with 5-HT(7) receptors? Neuronal connections in the medial geniculate body of the guinea-pig. Proconvulsant effect of aminophylline on cortical epileptic afterdischarges varies during ontogeny Quinolinic acid enhances permeability of rat brain microvessels to plasma albumin. Temporal and spatial expression of the cell-cycle regulator cul-1 in Drosophila and its stimulation by radiation-induced apoptosis. Ultrastructure of nuclei of cisplatin-treated C6 glioma cells undergoing apoptosis. Understanding hippocampal activity by using purposeful behavior: place navigation induces place cell discharge in both task-relevant and task-irrelevant spatial reference frames. Ultrastructure and innervation of regenerated intrafusal muscle fibres in heterochronous isografts of the fast rat muscle. Activation of a delayed-early gene encoding MHR3 by the ecdysone receptor heterodimer EcR-B1-USP-1 but not by EcR-B1-USP-2. Acoustically and electrically evoked contralateral suppression of otoacoustic emissions in guinea pigs. Insect clocks: What are they telling us besides time? The interaction of immunomodulator muramyl dipeptide with peripheral 5-HT receptors: overview of the current state. Glial depolarization evokes a larger potassium accumulation around oligodendrocytes than around astrocytes in gray matter of rat spinal cord slices. Glial swelling and astrogliosis produce diffusion barriers in the rat spinal cord. A new member of the AKH/RPCH family that stimulates locomotory activity in the firebug, Pyrrhocoris apterus (Heteroptera). Different effects of melatonin pretreatment on cAMP and LH responses of the neonatal rat pituitary cells. The effect of carbachol and alfa-bungarotoxin on the frequency of miniature endplate potentials at the frog neuromuscular junction. Effect of nitric oxide and NO synthase inhibition on nonquantal acetylcholine release in the rat diaphragm. Differences in gonadotropin-releasing hormone-induced calcium signaling between melatonin-sensitive and melatonin-insensitive neonatal rat gonadotrophs. Evidence for a tandem two-site model of ligand binding to muscarinic acetylcholine receptors. Discharge properties of neurons in subdivisions of the medial geniculate body of the guinea pig. Interstrain differences in cognitive functions in rats in relation to status epilepticus. Perireceptor and receptor events in olfaction. Comparison of concentration andflux detectors: a modeling study. Place recognition monitored by location-driven operant responding during passive transport of the rat over a circular trajectory. The place preference task: A new tool for studying the relation between behavior and place cell activity in rats. Participation of electrogenic Na+-K+-ATPase in the membrane potential of earthworm body wall muscles. Past, present and future of psychoneuroimmunology. Retinal ganglion cells regenerating through the peripheral nerve graft retain their electroretinographic responses and mediate light-induced behavior. Sensorimotor synchronization:the impact of temporally displaced auditory feedback. Spatilal distribution of spermine/spermidine content and K+-current rectification in frog retinal glial (Muller) cells. Response properties of neurons in the central nucleus and external and dorsal cortices of the inferior colliculus in guinea pig.
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