About: MDP and 5-HT receptors. Does MDP interact with 5-HT(7) receptors?

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About: MDP and 5-HT receptors. Does MDP interact with 5-HT(7) receptors? Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	A possible interaction of immunomodulator muramyl dipeptide (MDP) with 5-HT(7) (5-hydroxytryptamine) receptors was investigated. The activation of 5-HT(7) receptors relaxes the guinea-pig distal ileum. The whole ileum segments were, therefore, cut anddd placed into the bath. The preparations were precontracted by substance P and potently relaxed by adding incremental concentrations of 5-carboxamidotryptamine (5-CT) (0.01-3.2 microM), less potently by 5-hydroxytryptamine (5-HT) (1-100 microM). The p A possible interaction of immunomodulator muramyl dipeptide (MDP) with 5-HT(7) (5-hydroxytryptamine) receptors was investigated. The activation of 5-HT(7) receptors relaxes the guinea-pig distal ileum. The whole ileum segments were, therefore, cut anddd placed into the bath. The preparations were precontracted by substance P and potently relaxed by adding incremental concentrations of 5-carboxamidotryptamine (5-CT) (0.01-3.2 microM), less potently by 5-hydroxytryptamine (5-HT) (1-100 microM). The p (en)
Title	MDP and 5-HT receptors. Does MDP interact with 5-HT(7) receptors? MDP and 5-HT receptors. Does MDP interact with 5-HT(7) receptors? (en)
skos:prefLabel	MDP and 5-HT receptors. Does MDP interact with 5-HT(7) receptors? MDP and 5-HT receptors. Does MDP interact with 5-HT(7) receptors? (en)
skos:notation	RIV/67985947:_____/00:24003002!RIV/2001/GA0/A24001/N
http://linked.open.../vavai/riv/strany	587
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(GA305/99/1393), P(KSK2011602)
http://linked.open...iv/cisloPeriodika	8
http://linked.open...vai/riv/dodaniDat	2001
http://linked.open...aciTvurceVysledku	Mašek, Karel Ševčík, Jan Růžička, Vladimír Slánský, Josef
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Farmakologický ústav AV ČR
http://linked.open...dnocenehoVysledku	716804
http://linked.open...ai/riv/idVysledku	RIV/67985947:_____/00:24003002
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[0F6AA0306AC2]
http://linked.open...i/riv/nazevZdroje	International Journal of Immunopharmacology
http://linked.open...in/vavai/riv/obor	FR
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	The investigation of the participation of novel 5-HT receptor types in the mechanism of neuroimmunopharmacological effects of muramylpeptides Brain and nervous systems
http://linked.open...UplatneniVysledku	2000
http://linked.open...v/svazekPeriodika	22
http://linked.open...iv/tvurceVysledku	Mašek, Karel Ševčík, Jan Růžička, Vladimír Slánský, Josef
issn	0192-0561
number of pages	9 (xsd:int)

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